Evidence map›Paper›PMID 25789063›Full record

ArticleOncology letters2015

Insufficient radiofrequency ablation promotes human hepatoma SMMC7721 cell proliferation by stimulating vascular endothelial growth factor overexpression.

Zhining Liu, Hongliang Dai, Guizhi Jia, Yuhong Li, Xin Liu, Weidong Ren

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhining LiuUltrasound Department, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110004, P.R. China.
Hongliang DaiSchool of Nursing, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Guizhi JiaDepartment of Biochemistry and Molecular Biology, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Yuhong LiUltrasound Department, First Affiliated Hospital, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Xin LiuClinical Laboratory, First Affiliated Hospital, Liaoning Medical University, Jinzhou, Liaoning 121001, P.R. China.
Weidong RenUltrasound Department, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110004, P.R. China.
Jinzhou Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aims of the current study were to investigate the influence of insufficient radiofrequency ablation (RFA) on the cell proliferation of the human hepatocellular carcinoma (HCC) cells, SMMC7721, and to elucidate the underlying mechanism. SMMC7721 cells were subjected to a 47°C treatment regimen to simulate insufficient RFA, in the presence or absence of KN93 [a specific inhibitor of Ca

Indexed as

Ca2+/calmodulin-dependent protein kinase IIextracellular signal-regulated kinaseradiofrequencySMMC7721

Identifiers

PMID25789063
PMCPMC4356410
OpenAlexW2023195241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.