Evidence map›Paper›PMID 25789044›Full record

ArticleOncology letters2015

Expression of the γ-phosphorylated histone H2AX in gastric carcinoma and gastric precancerous lesions.

Zhong Guo, Shuyan Pei, Tianbin Si, Jing Li, Chao Jiang, Shangbiao Li, Jin Zhao

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Upregulation of theGenes & diseases · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhong GuoLaboratory of Functional Science, Medical College of Northwest University for Nationalities, Lanzhou, Gansu 730030, P.R. China.
Shuyan PeiLaboratory of Functional Science, Medical College of Northwest University for Nationalities, Lanzhou, Gansu 730030, P.R. China.
Tianbin SiDepartment of Gynecologic Oncology, Gansu Cancer Hospital, Lanzhou, Gansu 730050, P.R. China.
Jing LiDepartment of Gynecologic Oncology, Gansu Cancer Hospital, Lanzhou, Gansu 730050, P.R. China.
Chao JiangLaboratory of Functional Science, Medical College of Northwest University for Nationalities, Lanzhou, Gansu 730030, P.R. China.
Shangbiao LiLaboratory of Functional Science, Medical College of Northwest University for Nationalities, Lanzhou, Gansu 730030, P.R. China.
Jin ZhaoLaboratory of Functional Science, Medical College of Northwest University for Nationalities, Lanzhou, Gansu 730030, P.R. China.
Northwest Minzu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The histone γH2AX is a marker of activated DNA damage that is overexpressed in various cancers and corresponding precursor lesions, indicating that γH2AX is a component in oncogenic transformation. The present study aimed to determine whether the immunohistochemical expression of γH2AX is involved in the progression between superficial gastritis (n=20), atrophic gastritis (n=24) and gastric carcinoma (n=79). There was no increase in γH2AX expression between superficial and atrophic gastritis, but there was a significant increase in γH2AX expression between these two conditions and gastric carcinoma (χ

Indexed as

atrophic gastritisgastric carcinomasuperficial gastritisγH2AX

Identifiers

PMID25789044
PMCPMC4356332
OpenAlexW2143995750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.