Evidence map›Paper›PMID 25789025›Full record

ArticleOncology letters2015

Identification of differentially-expressed genes by DNA methylation in cervical cancer.

Heun-Sik Lee, Jun Ho Yun, Junghee Jung, Young Yang, Bong-Jo Kim, Sung-Jong Lee, Joo Hee Yoon, Yong Moon, Jeong-Min Kim, Yong-Il Kwon

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  4. AhRR and PPP1R3C: Potential Prognostic Biomarkers for Serous Ovarian Cancer.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Heun-Sik LeeCenter for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Cheongju, Chungcheongbuk-do 363-951, Republic of Korea.
Jun Ho YunCenter for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Cheongju, Chungcheongbuk-do 363-951, Republic of Korea.
Junghee JungMacrogen Inc., Seoul 153-023, Republic of Korea.
Young YangCenter for Women's Disease, Department of Biological Science, Sookmyung Women's University, Seoul 140-742, Republic of Korea.
Bong-Jo KimCenter for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Cheongju, Chungcheongbuk-do 363-951, Republic of Korea.
Sung-Jong LeeDepartment of Obstetrics and Gynecology, Saint Vincent's Hospital, the Catholic University, Suwon, Gyeonggi-do 442-723, Republic of Korea.
Joo Hee YoonDepartment of Obstetrics and Gynecology, Saint Vincent's Hospital, the Catholic University, Suwon, Gyeonggi-do 442-723, Republic of Korea.
Yong MoonDepartment of Public Health Administration, Namseoul University, Cheonan, Chungcheongnam-do 331-707, Republic of Korea.
Jeong-Min KimCenter for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Cheongju, Chungcheongbuk-do 363-951, Republic of Korea.
Yong-Il KwonDepartment of Obstetrics and Gynecology, Kangdong Sacred Heart Hospital, Hallym University Medical Center, Seoul 134-701, Republic of Korea.
Korea National Institute of Health · KRKangdong Sacred Heart Hospital · KRMacrogen (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To identify novel cervical cancer-related genes that are regulated by DNA methylation, integrated analyses of genome-wide DNA methylation and RNA expression profiles were performed using the normal and tumor regions of tissues from four patients; two with cervical cancer and two with pre-invasive cancer. The present study identified 19 novel cervical cancer-related genes showing differential RNA expression by DNA methylation. A number of the identified genes were novel cervical cancer-related genes and their differential expression was confirmed in a publicly available database. Among the candidate genes, the epigenetic regulation and expression of three genes,

Indexed as

cervical cancerDNA methylationepigeneticsintegrated analysisRNA expression

Identifiers

PMID25789025
PMCPMC4356325
OpenAlexW2037075168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.