Evidence map›Paper›PMID 25788999›Full record

ArticleOncology letters2015

Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.

Chan-Chan Shan, Liang-Rong Shi, Mei-Qian Ding, Yi-Bei Zhu, Xiao-Dong Li, Bin Xu, Jing-Ting Jiang, Chang-Ping Wu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Resolvins suppress tumor growth and enhance cancer therapy.The Journal of experimental medicine · 2018
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chan-Chan ShanDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Liang-Rong ShiDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Mei-Qian DingDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Yi-Bei ZhuInstitute of Biotechnology, Soochow University, Suzhou, Jiangsu, P.R. China.
Xiao-Dong LiDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Bin XuDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Jing-Ting JiangDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Chang-Ping WuDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China ; Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, P.R. China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiofrequency ablation (RFA) causes coagulative necrosis of tumor tissue and the production of local tumor protein debris. These fragments of tumor protein debris contain a large number of various antigens, which can stimulate a specific cellular immune response. In the present study, dendritic cells (DCs) were loaded with tumor protein lysate antigens that were produced

Indexed as

antigen loadcoloncytokine-induced killer cellsdendritic cellsprotein lysatethermal ablation

Identifiers

PMID25788999
PMCPMC4356333
OpenAlexW1988803719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.