Evidence map›Paper›PMID 25788987›Full record

ArticleDiabetology & metabolic syndrome2014

High prevalence of diabetes and intermediate hyperglycemia - The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Maria Inês Schmidt, Juliana F Hoffmann, Maria de Fátima Sander Diniz, Paulo A Lotufo, Rosane Härter Griep, Isabela M Bensenor, José G Mill, Sandhi Maria Barreto, Estela M L Aquino, Bruce B Duncan

Registry-linked trialAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04732611 (Effects of Pilates Exercises Versus Walking on Mechanical and Vascular Variables of Individuals With Type 2 Diabetes Mellitus), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04732611 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effects of Pilates Exercises Versus Walking on Mechanical and Vascular Variables of Individuals With Type 2 Diabetes Mellitus: Randomized Clinical Trial

TypeinterventionalSponsorFederal University of Rio Grande do SulRan2021 to 2022Enrolled60ConditionsDiabetes Mellitus, Type 2ArmsPilates exercises, Walking protocol
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Subclinical atherosclerosis in rheumatoid arthritis: a case cohort analysis from ELSA-Brasil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
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  20. Eight-year change in carotid intima-media thickness and associated risk factors in adults with and without psoriasis - the ELSA-Brasil cohort study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Inês SchmidtPostgraduate Studies Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul, Av. Ramiro Barcelos, 2600/414, 90035-003 Porto Alegre, RS Brazil.
Juliana F HoffmannPostgraduate Studies Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul, Av. Ramiro Barcelos, 2600/414, 90035-003 Porto Alegre, RS Brazil.
Maria de Fátima Sander DinizFaculdade de Medicina, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Paulo A LotufoCenter for Clinical and Epidemiologic Research, University of São Paulo, São Paulo, Brazil.
Rosane Härter GriepLaboratory of Health and Environment Education, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Isabela M BensenorCenter for Clinical and Epidemiologic Research, University of São Paulo, São Paulo, Brazil.
José G MillDepartment of Physiological Sciences, Federal University of Espírito Santo, Vitória, Brazil.
Sandhi Maria BarretoFaculdade de Medicina, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Estela M L AquinoInstituto Saúde Coletiva, Federal University of Bahia, Salvador, Brazil.
Bruce B DuncanPostgraduate Studies Program in Epidemiology, School of Medicine, Federal University of Rio Grande do Sul, Av. Ramiro Barcelos, 2600/414, 90035-003 Porto Alegre, RS Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global burden of diabetes mellitus and other chronic diseases is high, and 80% of those with diabetes now live in low and middle income countries. Yet, little information is available regarding prevalence of diabetes and intermediate hyperglycemia in these countries, especially when a full range of diagnostic tests is employed. The purpose of this study is to provide a full accounting of these prevalences in a large, free-living Brazilian population.

methodsWe report baseline data (2008-2010) from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a cohort study of 15,105 civil servants aged 35-74 years. Diabetes mellitus was ascertained by self-report of diagnosis, medication use, fasting glucose, an oral glucose tolerance test, and/or glycated hemoglobin. Cut-offs for diabetes and intermediate hyperglycemia followed the recommendations of the World Health Organization and the American Diabetes Association. Adjusted prevalences were estimated through logistic regression.

findingsWith this full accounting, 19.7% (19.0%-20.3%) had diabetes mellitus, 50.4% being previously undiagnosed. Frequencies of intermediate hyperglycemia according to various criteria ranged from 16.1% to 52.6%. Diabetes or intermediate hyperglycemia was present in 79.1% of participants when using the most comprehensive definitions. The burden was greatest in the elderly, the obese, non-whites, and those with less formal education (p < 0.001).

interpretationThat four of every five free-living individuals aged 35-74 years working in selected public institutions in six Brazilian state capitals presented either diabetes or intermediate hyperglycemia highlights the advanced stage of the obesity - diabetes epidemic in urban Brazil and indicates the need for urgent action.

Indexed as

BrazilDiabetes mellitusHyperglycemiaPrediabetic statePrevalence

Identifiers

PMID25788987
PMCPMC4363046

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.