ArticleNeural regeneration research2015
Therapeutic effects of different durations of acupuncture on rats with middle cerebral artery occlusion.
Article in Neural regeneration research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- The design and reporting of sham acupuncture and its association with the efficacy in acupuncture randomized controlled trials for migraine.BMC complementary medicine and therapies · 2026Article
- Clinical efficacy of DSA-based features in predicting outcomes of acupuncture intervention on upper limb dysfunction following ischemic stroke.Chinese medicine · 2024Article
- Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.Brain sciences · 2024Article
- Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- The immunomodulatory mechanism of acupuncture treatment for ischemic stroke: research progress, prospects, and future direction.Frontiers in immunology · 2024Review
- Manual acupuncture for neuromusculoskeletal disorders: The selection of stimulation parameters and corresponding effects.Frontiers in neuroscience · 2023Review
- Potential mechanisms of acupuncture in enhancing cerebral perfusion of ischemic stroke.Frontiers in neurology · 2022Review
- Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Sijunzi decoction may decrease apoptosis via stabilization of the extracellular matrix following cerebral ischaemia-reperfusion in rats.Experimental and therapeutic medicine · 2019Article
- Reporting items for systematic reviews and meta-analyses of acupuncture: the PRISMA for acupuncture checklist.BMC complementary and alternative medicine · 2019Article
- The Effect of Moxibustion Stimulation on Local and Distal Skin Temperature in Healthy Subjects.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Acupuncture and neuroregeneration in ischemic stroke.Neural regeneration research · 2018Review
- Mechanisms of Acupuncture Therapy for Cerebral Ischemia: an Evidence-Based Review of Clinical and Animal Studies on Cerebral Ischemia.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2017Review
- Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats.Experimental and therapeutic medicine · 2017Article
- Magnetic stimulation at Neiguan (PC6) acupoint increases connections between cerebral cortex regions.Neural regeneration research · 2016Article
- Is sham acupuncture as effective as traditional Chinese acupuncture? It's too early to say.Chinese journal of integrative medicine · 2016Review
- Large-conductance Ca(2+)-activated K(+) channel involvement in suppression of cerebral ischemia/reperfusion injury after electroacupuncture at Shuigou (GV26) acupoint in rats.Neural regeneration research · 2016Article
- The Effect of Acupuncture on the Motor Function and White Matter Microstructure in Ischemic Stroke Patients.Evidence-based complementary and alternative medicine : eCAM · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acupuncture is regarded as an effective therapy for cerebral ischemia. Different acupuncture manipulations and durations may result in different therapeutic effects. In the present study, the Neiguan (PC6) acupoint of rats with occluded middle cerebral arteries was needled at a fixed frequency (3 Hz) with different durations, i.e., 5, 60 and 180 seconds under a twisting-rotating acupuncture method. Results showed that different durations of acupuncture had different therapeutic effects, with 60 seconds yielding a better therapeutic effect than the other two groups. This duration of treatment demonstrated rapid cerebral blood flow, encouraging recovery of neurological function, and small cerebral infarct volume. Experimental findings indicated that under 3 Hz frequency, the treatment of needling Neiguan for 60 seconds is effective for ischemic stroke.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.