Evidence map›Paper›PMID 25788921›Full record

ArticleNeural regeneration research2015

Large animal models of human cauda equina injury and repair: evaluation of a novel goat model.

Wen-Tao Chen, Pei-Xun Zhang, Feng Xue, Xiao-Feng Yin, Cao-Yuan Qi, Jun Ma, Bo Chen, You-Lai Yu, Jiu-Xu Deng, Bao-Guo Jiang

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wen-Tao ChenDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Pei-Xun ZhangDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Feng XueDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Xiao-Feng YinDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Cao-Yuan QiDepartment of Radiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
Jun MaDepartment of Radiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
Bo ChenDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
You-Lai YuDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Jiu-Xu DengDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Bao-Guo JiangDepartment of Trauma and Orthopedics, Peking University People's Hospital, Beijing, China.
Peking University · CNPeking University People's Hospital · CNBeijing Tian Tan Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous animal studies of cauda equina injury have primarily used rat models, which display significant differences from humans. Furthermore, most studies have focused on electrophysiological examination. To better mimic the outcome after surgical repair of cauda equina injury, a novel animal model was established in the goat. Electrophysiological, histological and magnetic resonance imaging methods were used to evaluate the morphological and functional outcome after cauda equina injury and end-to-end suture. Our results demonstrate successful establishment of the goat experimental model of cauda equina injury. This novel model can provide detailed information on the nerve regenerative process following surgical repair of cauda equina injury.

Indexed as

animal modeldiagnosisdiffusion tensor imagingfiber bundlegoatinjurymagnetic resonance imagingnerve regenerationneural regenerationneuroimagingNSFC grantsphysiologyradiographyspinal cord injury

Identifiers

PMID25788921
PMCPMC4357118
OpenAlexW2094152810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.