Evidence map›Paper›PMID 25788489›Full record

ArticleBiology letters2015

Relationship between amino acid changes in mitochondrial ATP6 and life-history variation in anguillid eels.

Magnus W Jacobsen, José Martin Pujolar, Michael M Hansen

Open access · greenAbstract read
In one paragraph

Article in Biology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trends of Eurasian Perch (Animals : an open access journal from MDPI · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Magnus W JacobsenDepartment of Bioscience, Aarhus University, Ny Munkegade 114, Aarhus C 8000, Denmark magnus.jacobsen@bios.au.dk.
José Martin PujolarDepartment of Bioscience, Aarhus University, Ny Munkegade 114, Aarhus C 8000, Denmark.
Michael M HansenDepartment of Bioscience, Aarhus University, Ny Munkegade 114, Aarhus C 8000, Denmark.
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial genes are part of the oxidative phosphorylation pathway and important for energy production. Although evidence for positive selection at the mitochondrial level exists, few studies have investigated the link between amino acid changes and phenotype. Here we test the hypothesis that differences in two life-history related traits, migratory distance between spawning and foraging areas and larval phase duration, are associated with divergent selection within the mitochondrial ATP6 gene in anguillid eels. We compare amino acid changes among 18 species with the sequence of the putative ancestral species, believed to have shown short migratory distance and larval phase duration. We find positive correlations between both life-history related traits and (i) the number of amino acid changes and (ii) the strength of the combined physico-chemical and structural changes at positions previously identified as candidates for positive selection. This supports a link between genotype and phenotype driven by positive selection at ATP6.

Indexed as

Adaptation, BiologicalAmino Acid SequenceAnguillaAnimal MigrationAnimalsDNA, MitochondrialGenotypeLarvaLife Cycle StagesMitochondriaMitochondrial Proton-Translocating ATPasesPhenotypePhylogenyReproductionDNA, MitochondrialMitochondrial Proton-Translocating ATPasesanguillid eelsATP6positive selection

Identifiers

PMID25788489
PMCPMC4387500
OpenAlexW1981853978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.