ReviewCritical reviews in biochemistry and molecular biology2015
Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins.
Review in Critical reviews in biochemistry and molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed.
- Munc18 modulates syntaxin phase separation to promote exocytosis.Nature neuroscience · 2026Article
- SNARE-Mediated Membrane Fusion Probed Using a Synthetic Organelle in the Living Bacterium.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Molecular structures and function of the autophagosome-lysosome fusion machinery.Autophagy reports · 2024Article
- The function of VAMP2 in mediating membrane fusion: An overview.Frontiers in molecular neuroscience · 2022Review
- Selected tools to visualize membrane interactions.European biophysics journal : EBJ · 2021Review
- In vitro single vesicle fusion assays based on pore-spanning membranes: merits and drawbacks.European biophysics journal : EBJ · 2021Review
- The Membrane Interaction of Alpha-Synuclein.Frontiers in cellular neuroscience · 2021Review
- Fusion Pore Formation Observed during SNARE-Mediated Vesicle Fusion with Pore-Spanning Membranes.Biophysical journal · 2020Article
- Fusion of Bipolar Tetraether Lipid Membranes Without Enhanced Leakage of Small Molecules.Scientific reports · 2019Article
- Search for a minimal machinery for CaNeuroscience · 2019Article
- Single-vesicle measurement of protein-induced membrane tethering.Colloids and surfaces. B, Biointerfaces · 2019Article
- CaTrends in cell biology · 2018Review
- Mechanism of neurotransmitter release coming into focus.Protein science : a publication of the Protein Society · 2018Review
- The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion.EMBO reports · 2018Article
- Molecular Mechanisms of Fast Neurotransmitter Release.Annual review of biophysics · 2018Review
- Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 CProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion.Nature protocols · 2017Article
- Article
- A Membrane-Fusion Model That Exploits a β-to-α Transition in the Hydrophobic Domains of Syntaxin 1A and Synaptobrevin 2.International journal of molecular sciences · 2017Article
- Regulation of Exocytotic Fusion Pores by SNARE Protein Transmembrane Domains.Frontiers in molecular neuroscience · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Proteoliposomes have been widely used for in vitro studies of membrane fusion mediated by synaptic proteins. Initially, such studies were made with large unsynchronized ensembles of vesicles. Such ensemble assays limited the insights into the SNARE-mediated fusion mechanism that could be obtained from them. Single particle microscopy experiments can alleviate many of these limitations but they pose significant technical challenges. Here we summarize various approaches that have enabled studies of fusion mediated by SNAREs and other synaptic proteins at a single-particle level. Currently available methods are described and their advantages and limitations are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.