ArticleDer Nervenarzt2015
[Sarcopenia and frailty in neurology].
Article in Der Nervenarzt, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Sarcopenia and frailty in Parkinson's disease: A cross-sectional analytical study.Pakistan journal of medical sciences · 2026Article
- What contributes most to the SPPB and its subscores in hospitalized geriatric patients: an ICF model-based approach.BMC geriatrics · 2022Article
- [Clinical importance of the detection of frailty].Zeitschrift fur Gerontologie und Geriatrie · 2021Article
- Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study.BMC geriatrics · 2020Observational
- Appendicular skeletal muscle mass: A more sensitive biomarker of disease severity than BMI in adults with mitochondrial diseases.PloS one · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Sarcopenia and frailty are common geriatric syndromes and are associated with adverse health outcome and impaired health-related quality of life. Co-occurrences of these two syndromes with age-related neurological diseases are potentially high but not well investigated. Moreover, it is not well understood how these syndromes interact with neurological diseases, such as Parkinson's disease, Alzheimer's disease and stroke. This article introduces the currently most accepted concepts of sarcopenia and frailty, discusses the potential relevance of the syndromes for geriatric patients and presents examples of studies that investigated potential interactions between these geriatric and neurological syndromes and conditions. First results indicate that (i) the co-occurrence of these geriatric syndromes and age-related neurological diseases is high, (ii) sarcopenia and frailty can influence the clinical state of neurological diseases to a relevant extent and (iii) at least some common causes and pathophysiological processes confer the geriatric and neurological conditions. In conclusion, profound knowledge about the interaction of sarcopenia, frailty and age-associated neurological conditions is currently not available. Such knowledge would have an enormous potential for improved therapy of these neurological conditions.
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Registered trials
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