Evidence map›Paper›PMID 25787703›Full record

ArticleInhalation toxicology2015

Study of cardiovascular disease biomarkers among tobacco consumers, part 1: biomarkers of exposure.

Leanne R Campbell, Buddy G Brown, Bobbette A Jones, Kristin M Marano, Michael F Borgerding

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Inhalation toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01692353 (Evaluation of Cardiovascular Disease Biomarkers in Exclusive Smokers and Exclusive Moist Snuff Consumers), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01692353 completednot on this map

Evaluation of Cardiovascular Disease Biomarkers in Exclusive Smokers and Exclusive Moist Snuff Consumers

TypeobservationalSponsorR.J. Reynolds Tobacco CompanyRan2008 to 2009Enrolled168ConditionsCardiovascular Disease, Cigarette SmokingArmsSubject's usual brand (UB) tobacco product
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Five-Day Changes in Biomarkers of Exposure Among Adult Smokers After Completely Switching From Combustible Cigarettes to a Nicotine-Salt Pod System.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Leanne R CampbellR.J. Reynolds Tobacco Company , Winston-Salem, NC , USA and.
Buddy G Brown
Bobbette A Jones
Kristin M Marano
Michael F Borgerding
Reynolds American (United States) · USResearch Applications (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A study was conducted to evaluate biomarkers of biological effect and physiological assessments related to cardiovascular disease (CVD) among adult male cigarette smokers (SMK), moist snuff consumers (MSC) and non-consumers of tobacco (NTC). Additionally, biomarkers of tobacco and tobacco smoke exposure (BoE) were measured in spot urines and are reported here. Except for the BoE to nicotine and NNK, BoE were generally greater in SMK compared with MSC, and BoE were generally not different in comparisons of MSC and NTC. Results demonstrated that MSC had lower systemic exposures to many harmful and potentially harmful constituents than SMK, which is consistent with epidemiological data that indicate a differential in CVD risk between these groups.

Indexed as

AdultBiomarkersCardiovascular DiseasesCross-Sectional StudiesHumansMaleMiddle AgedRisk FactorsSmokingTobacco Use DisorderBiomarkersCigarettesclinical studyCVDharmful and potentially harmful constituentsmoist snuffspot urines

Identifiers

PMID25787703
PMCPMC4496812
OpenAlexW2065409050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.