Evidence map›Paper›PMID 25787699›Full record

SynthesisPsycho-oncology2016

Relations of meaning in life and sense of coherence to distress in cancer patients: a meta-analysis.

Joseph G Winger, Rebecca N Adams, Catherine E Mosher

Open access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Psycho-oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 7 pooled it
20.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 7 syntheses or guidelines pooled it, 181 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of meaning-based psychotherapy on post-traumatic growth and death anxiety in patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  4. Meaning in Life and the Acceptance of Cancer: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  5. Psychological interventions to foster resilience in healthcare students.The Cochrane database of systematic reviews · 2020
    Pooled it
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  8. Trial
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  10. Examining the effect of peer helping in a coping skills intervention: a randomized controlled trial for advanced gastrointestinal cancer patients and their family caregivers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Trial
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  17. Qualitative study on the sense of meaning in life in uremic patients undergoing initial hemodialysis.International journal of qualitative studies on health and well-being · 2025
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joseph G WingerDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Rebecca N AdamsDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Catherine E MosherDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
University of Indianapolis · USIndiana University – Purdue University Indianapolis · US

Funding

Training in Research for Behavioral Oncology and Cancer Control ProgramR25CA117865 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2006 to 2015
$4.1M
Interdisciplinary Training in Cancer Prevention and ControlT32CA117865 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI Victoria Lee Champion, Catherine E Mosher · 2016 to 2026
$2.4M
Telephone Symptom Management for Advanced Lung Cancer Patients and CaregiversK07CA168883 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI MOSHER, CATHERINE E · 2013 to 2017
$682k
Research and Training for Behavioral Oncology InterventionsK05CA175048 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2014 to 2018
$484k
NCI NIH HHS K05 CA175048NCI NIH HHS K05CA175048NCI NIH HHS K07 CA168883NCI NIH HHS K07CA168883NCI NIH HHS R25 CA117865NCI NIH HHS R25 CA117865-06NCI NIH HHS T32 CA117865
6 · The paper itself

Abstract

objectiveCancer patients report high rates of distress. The related constructs of meaning in life (MiL) and sense of coherence (SOC) have long been recognized as important factors in the psychological adjustment to cancer; however, both constructs' associations with distress have not been quantitatively reviewed or compared in this population. Informed by Park's integrated meaning-making model and Antonovsky's salutogenic model, the goals of this meta-analysis were the following: (1) to compare the strength of MiL-distress and SOC-distress associations in cancer patients; and (2) to examine potential moderators of both associations (i.e., age, gender, ethnicity, religious affiliation, disease stage, and time since diagnosis).

methodsA literature search was conducted using electronic databases. Overall, 62 records met inclusion criteria. The average MiL-distress and SOC-distress associations were quantified as Pearson's r correlation coefficients and compared using a one-way ANOVA.

resultsBoth MiL and SOC demonstrated significant, negative associations with distress (r = -0.41, 95% CI: -0.47 to -0.35, k = 44; and r = -0.59, 95% CI: -0.67 to -0.51, k = 18, respectively). Moreover, the MiL-distress association was significantly smaller than the SOC-distress association (Qb  = 10.42, df = 1, p < 0.01). Neither association varied by the tested moderators.

conclusionsFindings provide support for the clinical relevance of MiL and SOC across demographic and medical subgroups of cancer patients. The strength of the SOC-distress association suggests that incorporating aspects of SOC (e.g., the perceived manageability of life circumstances) into meaning-centered interventions may improve their effectiveness for distressed cancer patients.

Indexed as

Personal SatisfactionSense of CoherenceAdaptation, PsychologicalAnalysis of VarianceHumansNeoplasmsRandomized Controlled Trials as TopicStress, Psychological

Identifiers

PMID25787699
PMCPMC4575247
OpenAlexW1546295878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.