Evidence map›Paper›PMID 25787035›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2015

The combination of abdominal obesity and high-sensitivity C-reactive protein predicts new-onset hypertension in the general Japanese population: the Tanno-Sobetsu study.

Mizue Fujii, Hirofumi Ohnishi, Shigeyuki Saitoh, Hiroshi Akasaka, Tetsuji Miura, Mitsuru Mori

Open access · bronzeAbstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Clinical significance of 'cardiometabolic memory': a systematic review of randomized controlled trials.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Pooled it
  2. Article
  3. White blood cell and platelet distribution widths are associated with hypertension: data mining approaches.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. High blood pressure and its relationship to adiposity in a school-aged population: body mass index vs waist circumference.Hypertension research : official journal of the Japanese Society of Hypertension · 2018
    Article
  8. The relationship between obesity and hypertension: an updated comprehensive overview on vicious twins.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Review
  9. Article
  10. Association between mean platelet volume and hypertension incidence.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  11. Preventive effect of Eucommia leaf extract on aortic media hypertrophy in Wistar-Kyoto rats fed a high-fat diet.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  12. Feeling the pressure: (patho) physiological mechanisms of weight gain and weight loss in humans.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Review
  13. Relations of body weight status in early adulthood and weight changes until middle age with hypertension in the Chinese population.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
    Article
  14. Article
  15. Abdominal obesity and hypertension: a double burden to the heart.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
    Article
  16. The need for noninvasive methods to monitor hemodynamics in hypertension therapy.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mizue Fujii1] Department of Public Health, Sapporo Medical University School of Medicine, Sapporo, Japan [2] Department of Nursing, Sapporo City University School of Nursing, Sapporo, Japan.
Hirofumi Ohnishi1] Department of Public Health, Sapporo Medical University School of Medicine, Sapporo, Japan [2] Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Shigeyuki SaitohDepartment of Basics and Clinical Medicine, Sapporo Medical University School of Health Science, Sapporo, Japan.
Hiroshi AkasakaDepartment of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Tetsuji MiuraDepartment of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Mitsuru MoriDepartment of Public Health, Sapporo Medical University School of Medicine, Sapporo, Japan.
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to examine whether the combination of abdominal obesity and high serum levels of high-sensitivity C-reactive protein (hsCRP) improves the prediction of new-onset hypertension in the general Japanese population. Participants in the Tanno-Sobetsu study, a prospective cohort study, were enrolled. Of 1516 subjects aged 30 years or older in 2002, those with hypertension or abnormal hsCRP levels were excluded, and the remaining 705 subjects were included in the present analyses. Abdominal obesity (AO) and high hsCRP levels were defined by the Japanese criteria of waist circumference and median hsCRP values, respectively. Subjects were followed up on for a maximum of 4.5 years, and the hazard ratio (HR) for new-onset hypertension was calculated using the Cox proportional hazard model. The HR for new-onset hypertension after adjustment for age, sex, fasting plasma glucose, alcohol intake, smoking, treatment for dyslipidemia and high normal blood pressure at baseline was significantly higher in the group with AO and high hsCRP (HR=1.44, 95% CI: 1.00-2.07) compared with the reference group, a group with no AO and low hsCRP; AO alone or high hsCRP alone was not associated with a significant increase in the HR. Similar trends for the increase in the HR by AO and high hsCRP were observed in separate analyses of men and women, although the differences did not reach statistical significance. Co-presence of AO and a high level of hsCRP is associated with a high risk for new-onset hypertension in the general population.

Indexed as

AdultAgedAsian PeopleBlood PressureC-Reactive ProteinFemaleHumansHypertensionIncidenceJapanMaleMiddle AgedObesity, AbdominalProportional Hazards ModelsProspective StudiesRisk FactorsC-Reactive Protein

Identifiers

PMID25787035
OpenAlexW2002667231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.