ArticleDrug delivery and translational research2012
Engineering solid lipid nanoparticles for improved drug delivery: promises and challenges of translational research.
Article in Drug delivery and translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Pharmacokinetics of a Single Subcutaneous Extended-Release Buprenorphine (Ethiqa XR) in Healthy Beagles.Journal of veterinary pharmacology and therapeutics · 2026Article
- Onset of Analgesia in Rats (Rattus norvegicus) for Three Buprenorphine Formulations.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Lipid-based Nanoparticles as Drug Delivery System for Modern Therapeutics.Pharmaceutical nanotechnology · 2026Review
- Pharmacokinetic Analysis of Sustained-Release Buprenorphine Formulations in Owl Monkeys (Aotus spp.).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Intranasal Delivery of Paclitaxel-Loaded Ligand Conjugated Polymeric Nanoparticles for Targeted Brain Delivery.AAPS PharmSciTech · 2025Article
- Formulation Design, Optimization, and Evaluation of Solid Lipid Nanoparticles Loaded With an Antiviral Drug Tenofovir Using Box-Behnken Design for Boosting Oral Bioavailability.Advances in pharmacological and pharmaceutical sciences · 2024Article
- Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus).Scientific reports · 2023Article
- A Review of Long-acting Parenteral Analgesics for Mice and Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Review
- Effectiveness of two extended-release buprenorphine formulations during postoperative period in neonatal rats.PloS one · 2022Article
- Extended-release Buprenorphine, an FDAindexed Analgesic, Attenuates Mechanical Hypersensitivity in Rats (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Pharmaceutical design of a delivery system for the bacteriocin lacticin 3147.Drug delivery and translational research · 2021Article
- Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Animal models and experimental medicine · 2021Article
- Challenges in the Physical Characterization of Lipid Nanoparticles.Pharmaceutics · 2021Review
- Nanocarriers-Mediated Drug Delivery Systems for Anticancer Agents: An Overview and Perspectives.International journal of nanomedicine · 2021Review
- QbD aided development of ibrutinib-loaded nanostructured lipid carriers aimed for lymphatic targeting: evaluation using chylomicron flow blocking approach.Drug delivery and translational research · 2020Article
- In vivo treatment of experimental neurocysticercosis with praziquantel nanosuspensions-a metabolic approach.Drug delivery and translational research · 2018Article
- Challenge in particle delivery to cells in a microfluidic device.Drug delivery and translational research · 2018Article
- A Long-Term Study of a Lipid-Buprenorphine Implant in Rats.Journal of veterinary medicine · 2018Article
- Subcutaneous Implants of a Cholesterol-Triglyceride-Buprenorphine Suspension in Rats.Journal of veterinary medicine · 2017Article
- Development of solid lipid nanoparticles containing total flavonoid extract fromInternational journal of nanomedicine · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanotechnology is expected to revolutionize existing drug delivery. Many nanostructured systems have been employed for drug delivery and yielded some promising results. Solid lipid nanoparticles (SLN) have been looked at as a potential drug carrier system since last two decades. SLN do not show biotoxicity as they are prepared from physiological lipids. SLN are especially useful in drug delivery as they can enhance the absorption of drugs and improves the bioavailability of both hydrophilic and lipophilic drugs. This paper presents an overview about the various classes of SLN, comparison with available drug carrier systems, different ways of production, in vivo fate and biodistribution and various applications of SLN. Besides, aspects of stability, hurdles and strategies for SLN manufacturing with potential of clinical translation are also discussed.
Identifiers
25787030What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.