Evidence map›Paper›PMID 25786905›Full record

ArticleSurgical endoscopy2015

Do we need antibiotic prophylaxis in endoscopic inguinal hernia repair? Results of the Herniamed Registry.

F Köckerling, R Bittner, D Jacob, C Schug-Pass, C Laurenz, D Adolf, T Keller, B Stechemesser

Open access · hybridAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018
    Guideline
  4. Article
  5. Article
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  9. Retrospective study of perioperative antimicrobial use in horses undergoing elective laparoscopy at a single institution.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024
    Article
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  15. Review
  16. Review
  17. [Evidence-based TEP technique].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

F KöckerlingDepartment of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstraße 6, 13585, Berlin, Germany. ferdinand.koeckerling@vivantes.de.
R BittnerWinghofer Medicum, Hernia Center, Winghofer Straße 42, 72108, Rottenburg am Neckar, Germany.
D JacobDepartment of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstraße 6, 13585, Berlin, Germany.
C Schug-PassDepartment of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstraße 6, 13585, Berlin, Germany.
C LaurenzDepartment of Surgery and Center for Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital, Neue Bergstraße 6, 13585, Berlin, Germany.
D AdolfStatConsult GmbH, Halberstädter Straße 40 a, 39112, Magdeburg, Germany.
T KellerStatConsult GmbH, Halberstädter Straße 40 a, 39112, Magdeburg, Germany.
B StechemesserHernia Center Cologne, PAN - Hospital, Zeppelinstraße 1, 50667, Cologne, Germany.
Charité - Universitätsmedizin Berlin · DEInfoConsult (Germany) · DEVivantes Klinikum · DEWinghofer Medicum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of antibiotic prophylaxis in inguinal hernia repair is a controversial issue. Accepted randomized controlled trials or registry data with specific analysis of endoscopic repaired patients do not exist. PATIENT AND

methodsThe data presented in this study compared the prospectively collected data from the Herniamed Registry on all patients who had undergone unilateral, bilateral or recurrent repair of inguinal hernias using either endoscopic or open techniques between September 1, 2009, and March 5, 2014. In total, 85,033 patients were enrolled. Of these patients, 48,201 (56.7 ) had an endoscopic and 36,832 (43.3%) an open repair. The target variables analyzed were impaired wound healing and deep infections with mesh involvement within 30 days after the operation.

resultsAnalysis of the patient group with endoscopic/laparoscopic inguinal hernia repair (n = 48,201) did not identify any significant influence of antibiotic prophylaxis on postoperative impaired wound healing, which occurred in 53 cases (p = 0.6431). Nor was it possible to identify any significant impact of antibiotic prophylaxis on the deep infections seen in 27 cases (p = 0.8409). Analysis of the open inguinal hernia repair group revealed that, unlike the laparoscopic/endoscopic group, antibiotic prophylaxis had a significant impact on the postoperative impaired wound healing and deep infection rates. The risk of postoperative impaired wound healing with antibiotic prophylaxis was significantly lower [OR 0.677 (0.479; 0.958), p = 0.027].

conclusionThe positive impact of the endoscopic/laparoscopic technique on avoidance of impaired wound healing and deep infections with mesh involvement is already so great that antibiotic prophylaxis has no additional benefit. In contrast, antibiotic prophylaxis should be administered for open inguinal hernia repair.

Indexed as

Antibiotic ProphylaxisLaparoscopyAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsFemaleHernia, InguinalHerniorrhaphyHumansMaleMiddle AgedPreoperative CareRegistriesSurgical Wound InfectionAnti-Bacterial AgentsAntibiotic prophylaxisEndoscopic inguinal hernia repairPostoperative complicationsTAPPTEPWound infection

Identifiers

PMID25786905
PMCPMC4648957
OpenAlexW2095324339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.