Evidence map›Paper›PMID 25786099›Full record

Observational studyKidney international2015

The risk of hospitalization and modality failure with home dialysis.

Rita S Suri, Lihua Li, Gihad E Nesrallah

Registry-linked trialOpen access · hybridAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Kidney international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03994133 (Contribution of Body Composition Monitor), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03994133 unknown statusnot on this mapstarted 2019, after this paper: background citation

Contribution of Body Composition Monitor (BCM) Among Patients Using Daily Home Dialysis With Low Dialysate Flow : French Study Cohort

TypeobservationalSponsorUniversity Hospital, CaenRan2019 to 2020Enrolled85ConditionsChronic Kidney Disease Requiring Chronic Dialysis, Hemodialysis, Home, Electric ImpedanceArmsMeasurement of the hydration state by bio-impedance spectroscopy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Home versus in-centre haemodialysis for people with kidney failure.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Risk of Major Adverse Cardiovascular Events in Home Dialysis Compared With In-Center Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Expanded home hemodialysis: case reports.International urology and nephrology · 2020
    Article
  14. Article
  15. Review
  16. Optimization of Dialysis Modality Transitions for Improved Patient Care.Canadian journal of kidney health and disease · 2019
    Review
  17. Hospitalizations in Dialysis Patients in Canada: A National Cohort Study.Canadian journal of kidney health and disease · 2018
    Article
  18. Article
  19. Re-evaluation of re-hospitalization and rehabilitation in renal research.Hemodialysis international. International Symposium on Home Hemodialysis · 2017
    Article
  20. Comparative effectiveness of home dialysis therapies: a matched cohort study.Canadian journal of kidney health and disease · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Rita S Suri1] Department of Medicine, Section of Nephrology, Centre de Recherche, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada [2] Division of Nephrology, Western University, London, Ontario, Canada.
Lihua LiDivision of Nephrology, Western University, London, Ontario, Canada.
Gihad E Nesrallah1] Department of Nephrology, Humber River Regional Hospital, Toronto, Ontario, Canada [2] The Li Ka Shing Knowledge Institute, Keenan Research Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Centre Hospitalier de l’Université de Montréal · CAHumber River Regional Hospital · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While home dialysis is being promoted, there are few comparative effectiveness studies of home-based modalities to guide patient decisions. To address this, we matched 1116 daily home hemodialysis (DHD) patients by propensity scores to 2784 contemporaneous USRDS patients receiving home peritoneal dialysis (PD), and compared hospitalization rates from cardiovascular, infectious, access-related or bleeding causes (prespecified composite), and modality failure risk. We performed similar analyses for 1187 DHD patients matched to 3173 USRDS patients receiving in-center conventional hemodialysis (CHD). The composite hospitalization rate was significantly lower with DHD than with PD (0.93 vs. 1.35/patient-year, hazard ratio=0.73 (95% CI=0.67-0.79)). DHD patients spent significantly fewer days in hospital than PD patients (5.2 vs. 9.2 days/patient-year), and significantly more DHD patients remained admission-free (52% DHD vs. 32% PD). In contrast, there was no significant difference in hospitalizations between DHD and CHD (DHD vs. CHD: 0.93 vs. 1.10/patient-year, hazard ratio 0.92 (0.85-1.00)). Cardiovascular hospitalizations were lower with DHD than with CHD (0.68 (0.61-0.77)), while infectious and access hospitalizations were higher (1.15 (1.04-1.29) and 1.25 (1.08-1.43), respectively). Significantly more PD than DHD patients switched back to in-center HD (44% vs. 15%; 3.4 (2.9-4.0)). In this prevalent cohort, home DHD was associated with fewer admissions and hospital days than PD, and a substantially lower risk of modality failure.

Indexed as

AdolescentAdultAgedAmbulatory Care FacilitiesCanadaCardiovascular DiseasesFemaleHemodialysis, HomeHospitalizationHumansInfectionsKidney Failure, ChronicLength of StayMaleMiddle AgedPeritoneal Dialysis

Identifiers

PMID25786099
PMCPMC4526768
OpenAlexW2064524480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.