Evidence map›Paper›PMID 25785977›Full record

ArticleThe New England journal of medicine2015

Why is there no generic insulin? Historical origins of a modern problem.

Jeremy A Greene, Kevin R Riggs

Abstract readHistorical Article
In one paragraph

Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. The commercialisation of insulin.Anaesthesia and intensive care · 2023
    Article
  7. The Nuances Surrounding Insulin Prescribing.Clinical diabetes : a publication of the American Diabetes Association · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Type 1 diabetes.Lancet (London, England) · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeremy A GreeneFrom the Division of General Internal Medicine (J.A.G., K.R.R.), the Department of the History of Medicine (J.A.G.), and the Berman Institute of Bioethics (K.R.R.), Johns Hopkins University School of Medicine, Baltimore.
Kevin R Riggs

Funding

BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
When is a Medicine Good Enough? The Problem of Therapeutic Equivalence, 1959-2009G13LM010890 · NLM · JOHNS HOPKINS UNIVERSITY · PI GREENE, JEREMY A · 2012 to 2014
$141k
NHLBI NIH HHS T32 HL007180NLM NIH HHS G13 LM010890
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drugs, GenericBiosimilar PharmaceuticalsDrug DiscoveryDrug IndustryHistory, 20th CenturyHistory, 21st CenturyHumansInsulinInsulin, Regular, HumanPatents as TopicBiosimilar PharmaceuticalsDrugs, GenericInsulinInsulin, Regular, Human

Identifiers

PMID25785977
PMCPMC13118486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.