Evidence map›Paper›PMID 25785973›Full record

ArticleThe New England journal of medicine2015

Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline.

Bruce L Miller, Bradford C Dickerson, Diane E Lucente, Mykol Larvie, Matthew P Frosch

Abstract readCase ReportsClinical Conference
In one paragraph

Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Frontotemporal Dementia.Neurologic clinics · 2016
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Bruce L Miller
Bradford C Dickerson
Diane E Lucente
Mykol Larvie
Matthew P Frosch

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
THE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYMAN, BRADLEY T. · 1985 to 2018
$42.1M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5M
PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MILLER, BRUCE L · 2004 to 2018
$27.1M
Pilot study of preclinical and prodromal frontotemporal degenerationR21NS084156 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI DICKERSON, BRADFORD C · 2013 to 2014
$472k
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062421NIA NIH HHS P50 AG005134NIA NIH HHS P50 AG023501NIA NIH HHS P50 AG05134NINDS NIH HHS NS084156NINDS NIH HHS R21 NS084156
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAtrophyFatal OutcomeFrontal LobeHumansMaleNeuroimagingPersonality DisordersPick Disease of the BrainPoint Mutationtau ProteinsTemporal LobeMAPT protein, humantau Proteins

Identifiers

PMID25785973
PMCPMC4795456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.