Evidence map›Paper›PMID 25785211›Full record

ArticleCase reports in hematology2015

A proven case of cutaneous rhizopus infection presenting with severe limb pain very soon after induction treatment in a patient with acute lymphoblastic leukemia.

Mehmet Sezgin Pepeler, Kadir Acar, Özlem Güzel Tunçcan, Ömer Uluoğlu, Ayşe Kalkancı, Hakan Atalar, Koray Kılıç, Gülsan Türköz Sucak

Abstract read
In one paragraph

Article in Case reports in hematology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehmet Sezgin PepelerDepartment of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey.
Kadir AcarDepartment of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey.
Özlem Güzel TunçcanDepartment of Infectious Disease, Gazi University Faculty of Medicine, Ankara, Turkey.
Ömer UluoğluDepartment of Pathology, Gazi University Faculty of Medicine, Ankara, Turkey.
Ayşe KalkancıDepartment of Microbiology, Gazi University Faculty of Medicine, Ankara, Turkey.
Hakan AtalarDepartment of Orthopedics, Gazi University Faculty of Medicine, Ankara, Turkey.
Koray KılıçDepartment of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey.
Gülsan Türköz SucakDepartment of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective and Importance. Invasive mucormycosis may complicate the course of patients with hematologic malignancies and has a very high mortality rate. Early diagnosis and aggressive approach combined with surgical and medical treatment have paramount importance for cure. Clinical Presentation. We report here a case of a patient with acute lymphoblastic leukemia presenting with a subcutaneous mass lesion which was sampled by an ultrasound guided needle biopsy. The pathology showed microorganisms with aseptate hyphae with wide, irregular walls and more or less branching with highly vertical angles which suggested a mold infection. The specimen was also cultured where Rhizopus spp. grew. Conclusion. Posaconazole 200 mg QID was commenced. She recovered from neutropenia and pain on day 20 of treatment. After 4 courses of hyper-CVAD chemotherapy, the remaining soft tissue mass was removed surgically and she underwent allogeneic HSCT from a full matched sibling donor under secondary prophylaxis.

Identifiers

PMID25785211
PMCPMC4345071

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