Evidence map›Paper›PMID 25785192›Full record

ReviewCardiovascular psychiatry and neurology2015

Cognitive Outcomes following Transcatheter Aortic Valve Implantation: A Systematic Review.

Ka Sing Paris Lai, Nathan Herrmann, Mahwesh Saleem, Krista L Lanctôt

Open access · hybridAbstract readReview
In one paragraph

Review in Cardiovascular psychiatry and neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Neurological Complications of Cardiological Interventions.Current neurology and neuroscience reports · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ka Sing Paris LaiNeuropsychopharmacology Research Group, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5 ; Faculty of Medicine, University of Toronto, Toronto, ON, Canada M5S 1A8.
Nathan HerrmannNeuropsychopharmacology Research Group, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5 ; Department of Psychiatry, University of Toronto, Toronto, ON, Canada M5T 1R8.
Mahwesh SaleemNeuropsychopharmacology Research Group, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5 ; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada M5S 1A8.
Krista L LanctôtNeuropsychopharmacology Research Group, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5 ; Department of Psychiatry, University of Toronto, Toronto, ON, Canada M5T 1R8 ; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada M5S 1A8.
Sunnybrook Health Science Centre · CAHealth Sciences Centre · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe aortic stenosis is the most common valvular heart disease in the elderly in the Western world and contributes to a large proportion of all deaths over the age of 70. Severe aortic stenosis is conventionally treated with surgical aortic valve replacement; however, the less invasive transcatheter aortic valve implantation (TAVI) is suggested for those at high surgical risk. While TAVI has been associated with improved survival and favourable outcomes, there is a higher incidence of cerebral microembolisms in TAVI patients. This finding is of concern given mechanistic links with cognitive decline, a symptom highly prevalent in those with cardiovascular disease. This paper reviews the literature assessing the possible link between TAVI and cognitive changes. Studies to date have shown that global cognition improves or remains unchanged over 3 months following TAVI while individual cognitive domains remain preserved over time. However, the association between TAVI and cognition remains unclear due to methodological limitations. Furthermore, while these studies have largely focused on memory, cognitive impairment in this population may be predominantly of vascular origin. Therefore, cognitive assessment focusing on domains important in vascular cognitive impairment, such as executive dysfunction, may be more helpful in elucidating the association between TAVI and cognition in the long term.

Identifiers

PMID25785192
PMCPMC4345202
OpenAlexW2054380156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.