ArticleInternational journal of clinical and experimental medicine2015
Orthotopic transplantation of decellularized liver scaffold in mice.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Details determining the success in establishing a mouse orthotopic liver transplantation model.World journal of gastroenterology · 2020Review
- Blended electrospinning with human liver extracellular matrix for engineering new hepatic microenvironments.Scientific reports · 2019Article
- Data on a novel liver bioscaffold (rDLS) generated from regenerative liver with activated extracellular matrix for functional liver regeneration.Data in brief · 2019Article
- Decellularized scaffolds in regenerative medicine.Oncotarget · 2016Review
- Exploring the memory of the extracellular matrix using MASH-derived decellularized scaffolds.Journal of tissue engineeringArticle
- Liver scaffolds obtained by decellularization: A transplant perspective in liver bioengineering.Journal of tissue engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
End-stage liver disease is a life threatening health problem to millions of people worldwide. Orthotopic liver transplantation is the only therapy for the definitive cure at the present time. However, persistent shortage in donor organs limits the opportunity for patients to receive this treatment. Liver tissue engineering aims to overcome this restriction by generating functional tissue constructs for treatment of individuals with the end-stage liver disease. Recently, a new strategy has emerged using the natural organ scaffold as a vehicle for liver tissue engineering. This involves preparation of decellularized scaffold containing the circulatory framework of the natural organ system. Currently, surgical performance of liver scaffold transplantation with end-to-side anastomosis of major vessels in small experimental animals, particularly in mice (mLBST), remains technically challenging. Here, we describe surgical techniques of mLBST that can be used for evaluation of engineered liver grafts in recipients.
Indexed as
Identifiers
25785034PMC4358489W2408052830What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.