ArticleOncoTargets and therapy2015
Single-nucleotide polymorphisms of microRNA processing machinery genes are associated with risk for gastric cancer.
Article in OncoTargets and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Pooled it
- Association of miRNA biosynthesis genesBioscience reports · 2018Pooled it
- Pan-Cancer Study on Variants of Canonical miRNA Biogenesis Pathway Components: A Pooled Analysis.Cancers · 2023Article
- Single nucleotide variants in microRNA biosynthesis genes in Mexican individuals.Frontiers in genetics · 2023Article
- A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.Nucleic acids research · 2021Article
- The association ofJournal of Cancer · 2020Article
- Association of microRNA biosynthesis genes XPO5 and RAN polymorphisms with cancer susceptibility: Bayesian hierarchical meta-analysis.Journal of Cancer · 2020Review
- Association of variants of miRNA processing genes with cervical precancerous lesion risk in a southern Chinese population.Bioscience reports · 2018Article
- The Role of Exportin-5 in MicroRNA Biogenesis and Cancer.Genomics, proteomics & bioinformatics · 2018Review
- Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.Journal of clinical laboratory analysis · 2018Article
- Association between SNPs in microRNA machinery genes and gastric cancer susceptibility, invasion, and metastasis in Chinese Han population.Oncotarget · 2017Article
- Gene expression study and pathway analysis of histological subtypes of intestinal metaplasia that progress to gastric cancer.PloS one · 2017Article
- Association ofOncoTargets and therapy · 2017Article
- Article
- Polymorphisms in GEMIN4 and AGO1 Genes Are Associated with the Risk of Lung Cancer: A Case-Control Study in Chinese Female Non-Smokers.International journal of environmental research and public health · 2016Article
- Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells.Oncotarget · 2016Article
- A polymorphism at the microRNA binding site in the 3'-untranslated region ofExperimental and therapeutic medicine · 2016Article
- Article
- MicroRNA biogenesis pathway genes polymorphisms and cancer risk: a systematic review and meta-analysis.PeerJ · 2016Article
- Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma.PloS one · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies demonstrate that microRNA-related single-nucleotide polymorphisms (miR-SNPs) are associated with the development of numerous human cancers. In this study, we investigated six miR-SNPs in microRNA processing machinery genes, including rs11077 of the XPO5 gene, rs14035 of the RAN gene, rs3742330 of the Dicer gene, rs9623117 of the TNRC6B gene, rs197412 of the GEMIN3 gene, and rs2740348 of the GEMIN4 gene, in gastric cancer patients and subsequently evaluated their potential roles in gastric cancer risk in a case control study. The results indicate that the C/C genotype of rs14035 from RAN, the A/A genotype of rs3742330 from Dicer, and the T/T genotype of rs9623117 from TNRC6B are significantly associated with gastric cancer risk. In conclusion, these miR-SNPs can be used as predictive biomarkers in gastric cancer.
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