ArticleAmerican journal of hypertension2015
Nocturnal Blood Pressure in Young Adults and Cognitive Function in Midlife: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Article in American journal of hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between ambulatory blood pressure monitoring patterns with cognitive function and risk of dementia: a systematic review and meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Nocturnal blood pressure rather than night-to-day blood pressure ratio is related to arterial stiffening in untreated young and middle-aged adults with non-dipper hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Trial
- No association between sleep apnea, nocturnal blood pressure dipping, and cognitive performance among Swedish adults aged 50-65 years.Journal of internal medicine · 2025Article
- Nocturnal blood pressure dipping, blood pressure variability, and cognitive function in early and middle-aged adults.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Management of nocturnal hypertension: An expert consensus document from Chinese Hypertension League.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Non-Dipping Blood Pressure or Nocturnal Hypertension: Does One Matter More?Current hypertension reports · 2024Review
- High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Blood pressure change and cognition in childhood and early adulthood: a systematic review.Therapeutic advances in chronic disease · 2022Review
- Sleep duration and 24-hour ambulatory blood pressure in adults not on antihypertensive medications.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Ambulatory blood pressure monitoring and neurocognitive function in children with primary hypertension.Pediatric nephrology (Berlin, Germany) · 2018Article
- Associations of Nocturnal Blood Pressure With Cognition by Self-Identified Race in Middle-Aged and Older Adults: The GENOA (Genetic Epidemiology Network of Arteriopathy) Study.Journal of the American Heart Association · 2017Article
- Review
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Authors and funding
12 authors.
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Abstract
backgroundNocturnal blood pressure (BP) is associated with risk for cardiovascular events. However, the relationship between nocturnal BP in young adults and cognitive function in midlife remains unclear.
methodsWe used data from the ambulatory BP monitoring substudy of the Coronary Artery Risk Development in Young Adults Study, including 224 participants (mean age 30 years, 45% men, 63% African Americans). At the 20-year follow-up, the Stroop test (executive function), Digit Symbol Substitution Test (psychomotor speed), and Rey Auditory Verbal Learning Test (verbal memory) were assessed.
resultsBaseline mean office, daytime, and nocturnal BP were 109/73, 120/74, and 107/59 mm Hg, respectively. Nocturnal BP dipping, calculated as (nocturnal systolic BP [SBP]--daytime SBP) × 100/daytime SBP, was divided into quartiles (Q1: -39.3% to -16.9%; Q2: -16.8% to -13.2%, Q3 [reference]: -13.1% to -7.8%, and Q4: -7.7% to +56.4%). In multiple regression analyses, the least nocturnal SBP dipping (Q4 vs. reference) and higher nocturnal diastolic BP level were associated with worse Stroop scores, with adjustments for demographic and clinical characteristics, and cumulative exposure to office BP during follow-up (β [standard error]: 0.37 [0.18] and 0.19 [0.07], respectively; all P < 0.05). Digit Symbol Substitution Test and Rey Auditory Verbal Learning Test were not significantly associated with nocturnal SBP dipping or nocturnal SBP/diastolic BP levels.
conclusionsAmong healthy young adults, less nocturnal SBP dipping and higher nocturnal diastolic BP levels were associated with lower executive function in midlife, independent of multiple measures of office BP during long-term follow-up.
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