ArticlePlant physiology2015
The Arabidopsis RNA-binding protein AtRGGA regulates tolerance to salt and drought stress.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 72 citations in OpenAlex.
- Grain amaranth genes coding for an RNA-binding and a small, unknown function protein, respectively, enhance thermotolerance when overexpressed inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2026Article
- The mRNA-binding protein HLN1 enhances drought stress tolerance by stabilizing the GAD2 mRNA in Arabidopsis.Stress biology · 2025Article
- The Regulatory Roles of RNA-Binding Proteins in Plant Salt Stress Response.Plants (Basel, Switzerland) · 2025Review
- Proteome Reprogramming and Acquired Stress Tolerance in Potato Cells Exposed to Acute or Stepwise Water Deficit.Plant, cell & environment · 2025Article
- Genome-wide analysis for root and leaf architecture traits associated with drought tolerance at the seedling stage in a highly ecologically diverse wheat population.Computational and structural biotechnology journal · 2024Article
- Adaptive divergence, historical population dynamics, and simulation of suitable distributions for Picea Meyeri and P. Mongolica at the whole-genome level.BMC plant biology · 2024Article
- SOS1 tonoplast neo-localization and the RGG protein SALTY are important in the extreme salinity tolerance of Salicornia bigelovii.Nature communications · 2024Article
- Genomic signatures of ecological divergence between savanna and forest populations of a Neotropical tree.Annals of botany · 2023Article
- Identification of genetic and biochemical mechanisms associated with heat shock and heat stress adaptation in grain amaranths.Frontiers in plant science · 2023Article
- Concentration and time-dependent amyloidogenic characteristics of intrinsically disordered N-terminal region ofFrontiers in microbiology · 2023Article
- Ribonomics Approaches to Identify RBPome in Plants and Other Eukaryotes: Current Progress and Future Prospects.International journal of molecular sciences · 2022Review
- The mRNA-binding proteome of a critical phase transition during Arabidopsis seed germination.The New phytologist · 2022Article
- Transcriptome Sequence Analysis of the Defense Responses of Resistant and Susceptible Cucumber Strains toFrontiers in plant science · 2022Article
- Heterologous Expression of ArabidopsisFrontiers in genetics · 2022Article
- Regulation and physiological function of proteins for heat tolerance in cowpea (Frontiers in plant science · 2022Article
- Phytophthora infestans RXLR effector Pi04089 perturbs diverse defense-related genes to suppress host immunity.BMC plant biology · 2021Article
- Genome-wide identification and functional characterization of the PheE2F/DP gene family in Moso bamboo.BMC plant biology · 2021Article
- The Landscape of RNA-Protein Interactions in Plants: Approaches and Current Status.International journal of molecular sciences · 2021Review
- Functional Roles of RNA-Binding Proteins in Plant Signaling.Life (Basel, Switzerland) · 2020Review
- DRT111/SFPS Splicing Factor Controls Abscisic Acid Sensitivity during Seed Development and Germination.Plant physiology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salt and drought stress severely reduce plant growth and crop productivity worldwide. The identification of genes underlying stress response and tolerance is the subject of intense research in plant biology. Through microarray analyses, we previously identified in potato (Solanum tuberosum) StRGGA, coding for an Arginine Glycine Glycine (RGG) box-containing RNA-binding protein, whose expression was specifically induced in potato cell cultures gradually exposed to osmotic stress. Here, we show that the Arabidopsis (Arabidopsis thaliana) ortholog, AtRGGA, is a functional RNA-binding protein required for a proper response to osmotic stress. AtRGGA gene expression was up-regulated in seedlings after long-term exposure to abscisic acid (ABA) and polyethylene glycol, while treatments with NaCl resulted in AtRGGA down-regulation. AtRGGA promoter analysis showed activity in several tissues, including stomata, the organs controlling transpiration. Fusion of AtRGGA with yellow fluorescent protein indicated that AtRGGA is localized in the cytoplasm and the cytoplasmic perinuclear region. In addition, the rgga knockout mutant was hypersensitive to ABA in root growth and survival tests and to salt stress during germination and at the vegetative stage. AtRGGA-overexpressing plants showed higher tolerance to ABA and salt stress on plates and in soil, accumulating lower levels of proline when exposed to drought stress. Finally, a global analysis of gene expression revealed extensive alterations in the transcriptome under salt stress, including several genes such as ASCORBATE PEROXIDASE2, GLUTATHIONE S-TRANSFERASE TAU9, and several SMALL AUXIN UPREGULATED RNA-like genes showing opposite expression behavior in transgenic and knockout plants. Taken together, our results reveal an important role of AtRGGA in the mechanisms of plant response and adaptation to stress.
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