ArticleLife (Basel, Switzerland)2015
The Anabaena sp. PCC 7120 Exoproteome: Taking a Peek outside the Box.
Article in Life (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Cyanobacteria-Derived Extracellular Vesicles: A Novel Frontier in Drug Delivery and Therapeutics.International journal of molecular sciences · 2025Review
- EXCRETE workflow enables deep proteomics of the microbial extracellular environment.Communications biology · 2024Article
- Screening of Lipid-Reducing Activity and Cytotoxicity of the Exometabolome from Cyanobacteria.Marine drugs · 2024Article
- Biomedical engineering utilizing living photosynthetic cyanobacteria and microalgae: Current status and future prospects.Materials today. Bio · 2024Review
- Article
- An ancient bacterial zinc acquisition system identified from a cyanobacterial exoproteome.PLoS biology · 2024Article
- Measuring the rate of NADPH consumption by glutathione reductase in the cytosol and mitochondria.PloS one · 2024Article
- Article
- Adaptation to an Intracellular Lifestyle by a Nitrogen-Fixing, Heterocyst-Forming Cyanobacterial Endosymbiont of a Diatom.Frontiers in microbiology · 2022Article
- Linear Six-Carbon Sugar Alcohols Induce Lysis ofFrontiers in microbiology · 2022Article
- Comparative Phenotypic Analysis ofJournal of microbiology and biotechnology · 2021Article
- The Under-explored Extracellular Proteome of Aero-Terrestrial Microalgae Provides Clues on Different Mechanisms of Desiccation Tolerance in Non-Model Organisms.Microbial ecology · 2021Article
- Specificities and functional coordination between the two Cas6 maturation endonucleases inRNA biology · 2020Article
- Extracellular Vesicles: An Overlooked Secretion System in Cyanobacteria.Life (Basel, Switzerland) · 2020Review
- Cyanobacteria-Derived Proline Increases Stress Tolerance inFrontiers in plant science · 2020Article
- Differential biochemical properties of three canonical Dps proteins from the cyanobacteriumThe Journal of biological chemistry · 2018Article
- A calcium-stimulated serine peptidase from a true-branching cyanobacterium,Physiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- The CyanobacteriumFrontiers in microbiology · 2018Article
- Light Regimes Shape Utilization of Extracellular Organic C and N in a Cyanobacterial Biofilm.mBio · 2016Article
- Cyanobacterial reuse of extracellular organic carbon in microbial mats.The ISME journal · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interest in examining the subset of proteins present in the extracellular milieu, the exoproteome, has been growing due to novel insights highlighting their role on extracellular matrix organization and biofilm formation, but also on homeostasis and development. The cyanobacterial exoproteome is poorly studied, and the role of cyanobacterial exoproteins on cell wall biogenesis, morphology and even physiology is largely unknown. Here, we present a comprehensive examination of the Anabaena sp. PCC 7120 exoproteome under various growth conditions. Altogether, 139 proteins belonging to 16 different functional categories have been identified. A large fraction (48%) of the identified proteins is classified as "hypothetical", falls into the "other categories" set or presents no similarity to other proteins. The evidence presented here shows that Anabaena sp. PCC 7120 is capable of outer membrane vesicle formation and that these vesicles are likely to contribute to the exoproteome profile. Furthermore, the activity of selected exoproteins associated with oxidative stress has been assessed, suggesting their involvement in redox homeostasis mechanisms in the extracellular space. Finally, we discuss our results in light of other cyanobacterial exoproteome studies and focus on the potential of exploring cyanobacteria as cell factories to produce and secrete selected proteins.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.