ArticleActa orthopaedica2015
Increased risk of revision for infection in rheumatoid arthritis patients with total hip replacements.
Article in Acta orthopaedica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Revision Risk Following Total Hip Arthroplasty in Patients With Rheumatoid Arthritis: A Cohort Study From the Australian Orthopaedic Association National Joint Replacement Registry.ANZ journal of surgery · 2026Article
- Ten-year hip and knee arthroplasty implant survival in patients with inflammatory arthritis receiving methotrexate monotherapy compared with osteoarthritis: a registry-based data linkage study.Scientific reports · 2026Article
- Risk factors for revision due to prosthetic joint infection following total knee arthroplasty based on 62,087 knees in the Finnish Arthroplasty Register from 2014 to 2020.Acta orthopaedica · 2023Article
- Estimating incidence rates of periprosthetic joint infection after hip and knee arthroplasty for osteoarthritis using linked registry and administrative health data.The bone & joint journal · 2022Article
- Revision and 90-day mortality following hip arthroplasty in patients with inflammatory arthritis and ankylosing spondylitis enrolled in the National Joint Registry for England and Wales.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2022Article
- [Periprosthetic and interprothetic fractures in patients with rheumatism : Characteristics of conservative and surgical treatment].Der Unfallchirurg · 2020Review
- Review
- Anti-rheumatic treatment and prosthetic joint infection: an observational study in 494 elective hip and knee arthroplasties.BMC musculoskeletal disorders · 2020Observational
- Article
- No effect of delivery on total hip replacement survival: a nationwide register study in Finland.Acta orthopaedica · 2019Article
- Influence of Fixation Methods on Prosthetic Joint Infection Following Primary Total Knee Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies.Journal of clinical medicine · 2019Article
- The benefits of collaboration: the Nordic Arthroplasty Register Association.EFORT open reviews · 2019Review
- Implant Fixation and Risk of Prosthetic Joint Infection Following Primary Total Hip Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies.Journal of clinical medicine · 2019Article
- [Complications in orthopedic rheumatology-characteristics of operative procedures].Der Orthopade · 2018Review
- Have the Causes of Revision for Total and Unicompartmental Knee Arthroplasties Changed During the Past Two Decades?Clinical orthopaedics and related research · 2017Article
- Variation in Prosthetic Joint Infection and treatment strategies during 4.5 years of follow-up after primary joint arthroplasty using administrative data of 41397 patients across Australian, European and United States hospitals.BMC musculoskeletal disorders · 2017Article
- Revision total hip arthroplasty in the United States: national trends and in-hospital outcomes.International orthopaedics · 2016Article
- Clinical Factors, Disease Parameters, and Molecular Therapies Affecting Osseointegration of Orthopedic Implants.Current molecular biology reports · 2016Article
- Article
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Authors and funding
14 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMedical treatment of rheumatoid arthritis (RA) has changed dramatically over the last 15 years, including immune modulation. We investigated the risk of revision for infection after primary total hip replacement (THR) in patients with rheumatoid arthritis over a 16-year period, and compared it with that in THR patients with osteoarthritis (OA). PATIENTS AND
methodsWe identified 13,384 THRs in RA patients and 377,287 THRs in OA patients from 1995 through 2010 in a dataset from the Nordic Arthroplasty Register Association (NARA). Kaplan-Meier survival curves, with revision for infection as the endpoint, were constructed. Cox regression analyses were performed to calculate the relative risk (RR) of revision for infection adjusted for age, sex, fixation technique, and year of primary surgery.
resultsRA patients had a 1.3 times (95% CI 1.0-1.6) higher risk of revision for infection. After 2001, this risk increased more for RA patients than for OA patients. During the first 3 months and from 8 years postoperatively, the risk of revision for infection was higher in RA patients with THRs fixated with antibiotic-loaded cement than in corresponding OA patients.
interpretationWe found a slightly higher overall risk of revision for infection in RA patients than in OA patients, but this difference was only present after 2001. In THRs with antibiotic-loaded cement, the risk of very early and late infections leading to revision was higher in RA patients than in OA patients.
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