ArticlePloS one2015
Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Experimental detection of conformational transitions between forms of DNA: problems and prospects.Biophysical reviews · 2023Review
- Sequence dependence of transient Hoogsteen base pairing in DNA.PLoS computational biology · 2022Article
- Probing the Hydrogen-Bonding Environment of Individual Bases in DNA Duplexes with Isotope-Edited Infrared Spectroscopy.The journal of physical chemistry. B · 2021Article
- Slow motions in A·T rich DNA sequence.Scientific reports · 2020Article
- Atomistic insight into the kinetic pathways for Watson-Crick to Hoogsteen transitions in DNA.Nucleic acids research · 2019Article
- Infrared Spectroscopic Observation of a G-CAngewandte Chemie (International ed. in English) · 2019Article
- Novel Tautomerisation Mechanisms of the Biologically Important Conformers of the Reverse Löwdin, Hoogsteen, and Reverse Hoogsteen GFrontiers in chemistry · 2019Article
- Non-dissociative structural transitions of the Watson-Crick and reverse Watson-Crick А·Т DNA base pairs into the Hoogsteen and reverse Hoogsteen forms.Scientific reports · 2018Article
- The A·T(rWC)/A·T(H)/A·T(rH) ↔ A·T*(rwRSC advances · 2018Article
- Biologically important conformational features of DNA as interpreted by quantum mechanics and molecular mechanics computations of its simple fragments.Journal of molecular modeling · 2018Article
- Article
- Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.Nucleic acids research · 2017Article
- Robust IR-based detection of stable and fractionally populated G-CFEBS letters · 2017Article
- Metal-mediated base pairs in parallel-stranded DNA.Beilstein journal of organic chemistry · 2017Review
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Authors and funding
4 authors.
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Abstract
The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is favored in alternating AT sequences of DNA. Here we present new data for a different sequence, d(ATTAAT)2, which is also found in the Hoogsteen conformation. Thus we demonstrate that other all-AT sequences of DNA with a different sequence may be found in the Hoogsteen conformation. We conclude that any all-AT sequence might acquire this conformation under appropriate conditions. We also compare the detailed features of DNA in either the Hoogsteen or Watson-Crick conformations.
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