ArticlePloS one2015
Tissue distribution of the Ehrlichia muris-like agent in a tick vector.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Insights into tick-pathogen interactions - a single cell RNA sequencing approach of transcriptional changes during ehrlichial infection.bioRxiv : the preprint server for biology · 2026Article
- Behavioral manipulation ofmBio · 2025Article
- Tick extracellular vesicles in host skin immunity and pathogen transmission.Trends in parasitology · 2023Review
- A practical protocol to prepare paraffin-embedded whole tick histology sections.Ticks and tick-borne diseases · 2023Article
- A comparison of horizontal and transovarial transmission efficiency of Borrelia miyamotoi by Ixodes scapularis.Ticks and tick-borne diseases · 2022Article
- Identification of a rickettsial endosymbiont in a soft tick Ornithodoros turicata americanus.PloS one · 2022Article
- Article
- Ticks infesting dogs and cats in North America: Biology, geographic distribution, and pathogen transmission.Veterinary parasitology · 2021Review
- Enlisting thePathogens (Basel, Switzerland) · 2021Article
- Putative morphology of Neoehrlichia mikurensis in salivary glands of Ixodes ricinus.Scientific reports · 2020Article
- Article
- Mutational analysis of gene function in the Anaplasmataceae: Challenges and perspectives.Ticks and tick-borne diseases · 2019Article
- Efficient high-throughput molecular method to detect Ehrlichia ruminantium in ticks.Parasites & vectors · 2017Article
- Enhanced detection of Rickettsia species in Ixodes pacificus using highly sensitive fluorescence in situ hybridization coupled with Tyramide Signal Amplification.Ticks and tick-borne diseases · 2017Article
- Proposal to reclassify Ehrlichia muris as Ehrlichia muris subsp. muris subsp. nov. and description of Ehrlichia muris subsp. eauclairensis subsp. nov., a newly recognized tick-borne pathogen of humans.International journal of systematic and evolutionary microbiology · 2017Article
- Experimental evaluation of Peromyscus leucopus as a reservoir host of the Ehrlichia muris-like agent.Parasites & vectors · 2017Article
- Infection of Immature Ixodes scapularis (Acari: Ixodidae) by Membrane Feeding.Journal of medical entomology · 2016Article
- Co-Feeding Transmission of the Ehrlichia muris-Like Agent to Mice (Mus musculus).Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2016Article
- An Ixodes scapularis cell line with a predominantly neuron-like phenotype.Experimental & applied acarology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Human pathogens transmitted by ticks undergo complex life cycles alternating between the arthropod vector and a mammalian host. While the latter has been investigated to a greater extent, examination of the biological interactions between microbes and the ticks that carry them presents an equally important opportunity for disruption of the disease cycle. In this study, we used in situ hybridization to demonstrate infection by the Ehrlichia muris-like organism, a newly recognized human pathogen, of Ixodes scapularis ticks, a primary vector for several important human disease agents. This allowed us to assess whole sectioned ticks for the patterns of tissue invasion, and demonstrate generalized dissemination of ehrlichiae in a variety of cell types and organs within ticks infected naturally via blood feeding. Electron microscopy was used to confirm these results. Here we describe a strong ehrlichial affinity for epithelial cells, neuronal cells of the synganglion, salivary glands, and male accessory glands.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.