Evidence map›Paper›PMID 25781888›Full record

Trial reportPloS one2015

A new approach to improving healthcare personnel influenza immunization programs: a randomized controlled trial.

Larry W Chambers, Lois Crowe, Po-Po Lam, Donna MacDougall, Shelly McNeil, Virginia Roth, Kathryn Suh, Catherine Dalzell, Donna Baker, Hilary Ramsay and 3 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01207518 (Cluster RCT Evaluating the Effectiveness of "Successful Influenza Immunization Campaigns in Healthcare Organizations), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01207518 naunknown statusnot on this map

Cluster RCT Evaluating the Effectiveness of "Successful Influenza Immunization Campaigns in Healthcare Organizations: A Guide for Campaign Planners, Part of Optimizing Healthcare Workers Interpandemic Vaccine Uptake Study

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2010 to 2012Enrolled46ConditionsInfluenzaArmsIntervention Group, Control Group
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Larry W ChambersBruyère Research Institute, Ottawa, Ontario, Canada; Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Clinical and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Faculty of Health, York University, Toronto, Ontario, Canada; Institute for Clinical and Evaluative Sciences, Toronto, Ontario, Canada.
Lois CroweBruyère Research Institute, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Po-Po LamDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Donna MacDougallSt. Francis Xavier University, Antigonish, Nova Scotia, Canada; Canadian Center for Vaccinology, Halifax, Nova Scotia, Canada.
Shelly McNeilCanadian Center for Vaccinology, Halifax, Nova Scotia, Canada; Dalhousie University, Halifax, Nova Scotia, Canada.
Virginia RothThe Ottawa Hospital, Ottawa, Ontario, Canada.
Kathryn SuhThe Ottawa Hospital, Ottawa, Ontario, Canada.
Catherine DalzellBruyère Research Institute, Ottawa, Ontario, Canada.
Donna BakerBruyère Continuing Care, Ottawa, Ontario, Canada.
Hilary RamsayBruyère Research Institute, Ottawa, Ontario, Canada.
Sarah DeCoutereCanadian Center for Vaccinology, Halifax, Nova Scotia, Canada.
Heather L HallBruyère Continuing Care, Ottawa, Ontario, Canada.
Anne E McCarthyBruyère Research Institute, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; The Ottawa Hospital, Ottawa, Ontario, Canada.
Bruyère · CAOttawa Hospital · CADalhousie University · CAOttawa Hospital Research InstituteSt. Francis Xavier University · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

Canadian Institutes of Health Research 90189
6 · The paper itself

Abstract

backgroundHealthcare personnel influenza immunization rates remain sub-optimal. Following multiple studies and expert consultations, the "Successful Influenza Immunization Programs for Healthcare Personnel: A Guide for Program Planners" was produced. This trial assessed the impact of the Guide with facilitation in improving healthcare personnel influenza immunization rates in Canadian healthcare organizations.

methodsA sample of 26 healthcare organizations across six Canadian provinces (ON, MB, NS, BC, SK, NL) was randomized to Intervention (n=13) or Control groups (n=13). Baseline influenza immunization rates were obtained for 2008-2009; the study groups were followed over two subsequent influenza seasons. The Intervention group received the Guide, facilitation support through workshops for managers and ongoing support. The Control groups conducted programs as usual. The Groups were compared using their reported influenza healthcare personnel influenza immunization rates and scores from a program assessment questionnaire.

findingsTwenty-six organizations agreed to participate. 35% (9/26) of sites were acute care hospitals, 19% (5/26) continuing care, long-term care organizations or nursing homes, and 46% (12/26) were mixed acute care hospitals and long-term care or regional health authorities. The median rate of influenza immunization among healthcare personnel for the Intervention group was 43%, 44%, and 51% at three points in time respectively, and in the CONTROL GROUP: 62%, 57%, and 55% respectively. No significant differences were observed between the groups at the three points in time. However, there was a 7% increase in the median rates between the Baseline Year and Year Two in the Intervention group, and a 6% decrease in the CONTROL GROUP over the same time period, which was statistically significant (0.071 versus -0.058, p < 0.001).

interpretationThis pragmatic randomized trial of the Guide with facilitation of its implementation improved healthcare personnel immunization rates, but these rates continued to be sub-optimal and below rates achievable in programs requiring personnel to be immunized.

trial registrationClinicalTrials.gov NCT01207518.

Indexed as

Health PersonnelQuality of Health CareHumansImmunization ProgramsInfluenza, Human

Identifiers

PMID25781888
PMCPMC4363667
OpenAlexW2017846516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.