Evidence map›Paper›PMID 25781578›Full record

ArticleElectrophoresis2015

Development of the resolution theory for gradient insulator-based dielectrophoresis.

Paul V Jones, Mark A Hayes

Abstract read
In one paragraph

Article in Electrophoresis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Dielectrophoresis of proteins: experimental data and evolving theory.Analytical and bioanalytical chemistry · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul V JonesDepartment of Chemistry and Biochemistry, Arizona State University, AZ, USA.
Mark A HayesDepartment of Chemistry and Biochemistry, Arizona State University, AZ, USA.

Funding

Isolating Viral Particles from Whole BloodR03AI094193 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A, HOGUE, BRENDA G. · 2012 to 2013
$138k
Pathogen Isolation and Concentration for Phenotypic SubtypingR03AI099740 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A · 2012 to 2013
$138k
Isolation of Pathogenic ListeriaR03AI111361 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A · 2015 to 2016
$136k
NIAID NIH HHS R03 AI094193NIAID NIH HHS R03 AI099740NIAID NIH HHS R03 AI111361
6 · The paper itself

Abstract

New and important separations capabilities are being enabled by utilizing other electric field-induced forces besides electrophoresis, among these is dielectrophoresis. Recent works have used experimentally simple insulator-based systems that induce field gradients creating dielectrophoretic force in useful formats. Among these, juxtaposing forces can generate gradient-based steady-state separations schemes globally similar to isoelectric focusing. The system of interest is termed gradient insulator-based dielectrophoresis and can create extremely high resolution steady-state separations for particles four nanometers to ten micrometers in diameter, including nearly all important bioparticles (large proteins, protein aggregates, polynucleotides viruses, organelles, cells, bacteria, etc.). A theoretical underpinning is developed here to understand the relationship between experimental parameters and resolution and to identify the best expected resolution possible. According to the results, differences in particles (and bioparticles) as small as one part in 10(4) for diameter (subnanometer resolution for a one micrometer particle), one part in 10(8) for dielectrophoretic parameters (dielectrophoretic mobility, Clausius-Mossotti factor), and one part in 10(5) for electrophoretic mobility can be resolved. These figures of merit are generally better than any competing technique, in some cases by orders of magnitude. This performance is enabled by very strong focusing forces associated with localized gradients.

Indexed as

Models, TheoreticalElectrophoresisParticle SizeBioparticlesDielectrophoresisElectrokineticsResolution

Identifiers

PMID25781578
PMCPMC4500658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.