Evidence map›Paper›PMID 25781221›Full record

ArticleNutrients2015

Could a change in diet revitalize children who suffer from unresolved fatigue?

Tessa Gerjanne Steenbruggen, Sietske Johanna Hoekstra, Ellen José van der Gaag

Abstract readControlled Clinical Trial
In one paragraph

Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2016
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tessa Gerjanne SteenbruggenUniversity Medical Centre Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands. t.g.steenbruggen@gmail.com.
Sietske Johanna HoekstraUniversity Medical Centre Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands. hoekstrasj@gmail.com.
Ellen José van der GaagZiekenhuisgroep Twente, Hengelo, Geerdinksweg 141, 7555 DL Hengelo, The Netherlands. E.vdGaag@zgt.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many children deal with fatigue for which no proper treatment can be given. A possible explanation for their fatigue is a micro deficiency of minerals and vitamins. In this non-randomized controlled trial, we clinically evaluated symptoms of fatigue in children for whom a nutrient-rich diet was advised. A group of 98 children (2-18 years old) with unexplained symptoms of fatigue was examined. The dietary modifications consisted of green vegetables, beef, whole milk and full-fat butter. Children in the intervention group were asked to follow the diet for three months, whereas the control-group followed their normal diet. The primary outcome was symptoms of fatigue, as determined by a PedsQL Multidimensional Fatigue Scale, and secondary outcomes were compliance with the diet and BMI. Children, who followed the diet showed a significant decrease in the need to sleep (CI 0.83; 14.86, p = 0.03). They slept better through the night and took fewer naps. When analyzing components of the advised diet separately, a significant larger decrease in cognitive fatigue symptoms was seen for eating green vegetables according to the diet guidelines (CI 2.27; 30.63, p = 0.024). Furthermore, a lower need to sleep was seen when whole milk was consumed almost daily (CI 0.02; 14.62, p = 0.049). Our study showed that nutritional advice is an elegant, and effective method for decreasing some symptoms of medically unresolved fatigue in children.

Indexed as

DietFeeding BehaviorAnimalsBody Mass IndexChildChild, PreschoolCognitionFatigueFemaleFruitHumansMaleMilkMineralsNutrition PolicyPatient ComplianceMineralsVitamins

Identifiers

PMID25781221
PMCPMC4377893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.