ArticlePloS one2015
The value of MRI in the diagnosis of primary biliary cirrhosis and assessment of liver fibrosis.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Acquired ductopenia: an insight into imaging findings.Abdominal radiology (New York) · 2025Review
- Novel noninvasive indices for the assessment of liver fibrosis in primary biliary cholangitis.Biomedical reports · 2024Article
- CT and MR imaging of primary biliary cholangitis: a pictorial review.Insights into imaging · 2023Review
- Imaging Phenotypes and Evolution of Hepatic Langerhans Cell Histiocytosis on CT/MRI: A Retrospective Study of Clinical Cases and Literature Review.Bioengineering (Basel, Switzerland) · 2023Article
- Modern imaging of cholangitis.The British journal of radiology · 2021Review
- Magnetic resonance imaging features in 283 patients with primary biliary cholangitis.European radiology · 2020Article
- Article
- miR-200a controls hepatic stellate cell activation and fibrosis via SIRT1/Notch1 signal pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2017Article
- [Correlation of FibroTouch and FibroScan with the stage of primary biliary cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016Article
- Recent advances in the diagnosis and treatment of primary biliary cholangitis.World journal of hepatology · 2016Review
- Non-neoplastic cholangiopathies: an algorithmic approach.Radiologia brasileiraReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate MRI findings in patients with primary biliary cirrhosis (PBC) and to determine the value of MRI in the diagnosis of PBC and assessment of liver fibrosis. MATERIALS AND
methodsThis study reviewed the prevalence of MRI abnormalities seen in 45 PBC patients in the past four years, including 33 patients who underwent liver biopsy. Correlation between the MRI findings and the pathological stage was determined.
resultsThere were 33 patients who underwent liver biopsy. Twenty-five patients (75.8%) had non-homogeneous changes in the liver signal intensity, 25 (75.8%) had a periportal halo sign, and 29 (87.9%) had lymphadenopathy. The short axis of the enlarged lymph nodes was a mean of 1.2±0.3 cm. A strong positive correlation was observed between histological stage and the inhomogeneity of liver signal intensity (P<0.001). There were significant differences among the four histological stages based on the periportal halo sign (P=0.034), and the grading of the periportal halo sign was found to be significantly correlated with the histological stage (P<0.001). Grading of the periportal halo sign was significantly different at stage II versus III, and stage III versus IV; no significant difference was found between stages I and II. There were also no significant differences among the four histological states in the occurrence and size of enlarged lymph nodes (P=0.674 and P=0.394).
conclusionMRI is valuable in the diagnosis of PBC, and the periportal halo sign and liver signal intensity help to evaluate the degree of liver fibrosis.
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