ArticlePloS one2015
Dosimetric comparison of the simultaneous integrated boost in whole-breast irradiation after breast-conserving surgery: IMRT, IMRT plus an electron boost and VMAT.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Comparison of simultaneous integrated tumor bed boost and sequential boost during hypofractionated whole-breast irradiation after breast-conserving surgery.Clinical and translational radiation oncology · 2025Article
- Auto-segmentation of surgical clips for target volume delineation in post-lumpectomy breast cancer radiotherapy.BMC medical imaging · 2025Article
- Technical feasibility of delivering a simultaneous integrated boost in partial breast irradiation.Physics and imaging in radiation oncology · 2024Article
- Off-isocentric VMAT technique for breast cancer: Effective dose reduction to organs at risk and its applicability based on patient anatomy.Journal of applied clinical medical physics · 2024Article
- Comparison of helical and TomoDirect techniques with simultaneous integrated boost in early breast cancer patients.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Article
- Comparative analysis of dosimetry and predictive somatotype parameters of prone and supine whole-breast irradiation among Chinese women after breast-conserving surgery.Frontiers in oncology · 2022Article
- Which technique of positioning and immobilization is better for breast cancer patients in postmastectomy IMRT, single-pole or double-pole immobilization?Journal of applied clinical medical physics · 2019Article
- Chair Heterogeneity Index: Describing the dose heterogeneity inside the tumor volume where there is a boost volume.Scientific reports · 2018Article
- Critical appraisal of the role of volumetric modulated arc therapy in the radiation therapy management of breast cancer.Radiation oncology (London, England) · 2017Review
- Static beam tomotherapy as an optimisation method in whole-breast radiation therapy (WBRT).Journal of medical radiation sciences · 2017Article
- Advantages of a technique using two 50 degree arcs in simultaneous integrated boost radiotherapy for left-sidebreast cancer.Scientific reports · 2017Article
- Dosimetric comparison of simultaneous integrated boost with whole-breast irradiation for early breast cancer.PloS one · 2017Article
- Intensity modulated radiation therapy for breast cancer: current perspectives.Breast cancer (Dove Medical Press) · 2017Review
- Article
- Dosimetric Comparison of Sequential Boost versus Simultaneous Integrated Boost Intensity-modulated Delivery Techniques in Left-sided Breast Cancer Radiotherapy: A Planning Study.Journal of medical physicsArticle
- Dosimetric Comparison of SequentialIn vivo (Athens, Greece)Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the target volume coverage and doses to organs at risks (OARs) using three techniques that simultaneous integrated boost (SIB) in whole-breast irradiation (WBI) after breast-conserving surgery, including intensity-modulated radiation therapy (IMRT), IMRT plus an electron boost (IMRT-EB), and volumetric-modulated arc therapy (VMAT).
methodsA total of 10 patients with early-stage left-sided breast cancer after breast-conserving surgery were included in this study. IMRT, IMRT-EB and VMAT plans were generated for each patient.
resultsThe conformity index (CI) of the planning target volumes evaluation (PTV-Eval) of VMAT was significantly superior to those of IMRT and IMRT-EB (P < 0.05). The CI of the PTV Eval-boost of VMAT was better than that of IMRT (P = 0.018) and IMRT-EB (P < 0.001), while the CI of the PTV Eval-boost of IMRT was better than that of IMRT-EB (P = 0.002). The V5, V10 and Dmean in ipsilateral lung with VMAT were significantly higher than IMRT (P < 0.05) and IMRT-EB (P < 0.05). The Dmean, V5 and V10 in heart with VMAT were significantly greater than those of IMRT and IMRT-EB (P < 0.05). There was no significant difference in the OARs between IMRT and IMRT-EB (P > 0.05).
conclusionsConsidered the target volume coverage and radiation dose delivered to the OARs (especially the heart and lung), IMRT may be more suitable for the SIB in WBI than IMRT-EB and VMAT. Additional clinical studies with a larger sample size will be needed to assess the long-term feasibility and efficacy of SIB using different radiotherapy techniques.
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