ArticlePloS one2015
Continuous theta burst stimulation over the left dorsolateral prefrontal cortex decreases medium load working memory performance in healthy humans.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04864080 (Transdiagnostic Cognitive Biomarkers), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transdiagnostic Cognitive Biomarkers
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Combined noninvasive brain stimulation virtual reality for upper limb rehabilitation poststroke: A systematic review of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Assessing the Effects of Continuous Theta Burst Stimulation Over the Dorsolateral Prefrontal Cortex on Human Cognition: A Systematic Review.Frontiers in integrative neuroscience · 2020Pooled it
- State-dependent dual-site prefrontal TMS bidirectionally modulates working-memory accuracy.Frontiers in human neuroscience · 2026Article
- Noninvasive Therapies: A Forthcoming Approach to Parkinson's Treatment.CNS & neurological disorders drug targets · 2025Review
- Theta transcranial alternating current stimulation over the prefrontal cortex enhances theta power and working memory performance.Frontiers in psychiatry · 2024Article
- The Effect of Continuous Theta Burst Stimulation over the Right Dorsolateral Prefrontal Cortex on Cognitive Function and Emotional Regulation in Patients with Cerebral Small Vessel Disease.Brain sciences · 2023Article
- Enhancing Visuospatial Working Memory Performance Using Intermittent Theta-Burst Stimulation Over the Right Dorsolateral Prefrontal Cortex.Frontiers in human neuroscience · 2022Article
- No evidence for changes in GABA concentration, functional connectivity, or working memory following continuous theta burst stimulation over dorsolateral prefrontal cortex.Neuroimage. Reports · 2021Article
- The Role of Expectation and Beliefs on the Effects of Non-Invasive Brain Stimulation.Brain sciences · 2021Review
- Resting-state functional connectivity in the attention networks is not altered by offline theta-burst stimulation of the posterior parietal cortex or the temporo-parietal junction as compared to a vertex control site.Neuroimage. Reports · 2021Article
- Combining HF rTMS over the Left DLPFC with Concurrent Cognitive Activity for the Offline Modulation of Working Memory in Healthy Volunteers: A Proof-of-Concept Study.Brain sciences · 2020Article
- Working Memory Load-related Theta Power Decreases in Dorsolateral Prefrontal Cortex Predict Individual Differences in Performance.Journal of cognitive neuroscience · 2019Article
- The effects of individualised intermittent theta burst stimulation in the prefrontal cortex: A TMS-EEG study.Human brain mapping · 2019Article
- Continuous theta-burst stimulation over the dorsolateral prefrontal cortex inhibits improvement on a working memory task.Scientific reports · 2018Article
- Theta-burst stimulation causally affects side perception in the Deutsch's octave illusion.Scientific reports · 2018Article
- The relationship between dlPFC activity during unpredictable threat and COTranslational psychiatry · 2017Article
- No effects of transcranial DLPFC stimulation on implicit task sequence learning and consolidation.Scientific reports · 2017Article
- Theta-burst transcranial magnetic stimulation to the prefrontal or parietal cortex does not impair metacognitive visual awareness.PloS one · 2017Article
- Impact of Prefrontal Theta Burst Stimulation on Clinical Neuropsychological Tasks.Frontiers in neuroscience · 2017Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dorsolateral prefrontal cortex (DLPFC) plays a key role in working memory. Evidence indicates that transcranial magnetic stimulation (TMS) over the DLPFC can interfere with working memory performance. Here we investigated for how long continuous theta-burst stimulation (cTBS) over the DLPFC decreases working memory performance and whether the effect of cTBS on performance depends on working memory load. Forty healthy young subjects received either cTBS over the left DLPFC or sham stimulation before performing a 2-, and 3-back working memory letter task. An additional 0-back condition served as a non-memory-related control, measuring general attention. cTBS over the left DLPFC significantly impaired 2-back working memory performance for about 15 min, whereas 3-back and 0-back performances were not significantly affected. Our results indicate that the effect of left DLPFC cTBS on working memory performance lasts for roughly 15 min and depends on working memory load.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.