ReviewJournal of functional biomaterials2015
Chitin, chitosan, and its derivatives for wound healing: old and new materials.
Review in Journal of functional biomaterials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 338 citations in OpenAlex.
- Injectable rhBMP-2-loaded calcium phosphate cement and chitosan composite hydrogel for the repair of osteoporotic bone defects.BMC musculoskeletal disorders · 2026Article
- Marine-Origin Polysaccharides and Their Chemically Modified Derivatives as Sources of Advanced Biofunctional Materials for Biomedical Applications.Biomacromolecules · 2025Review
- Green synthesized ZnO and ZnO-based composites for wound healing applications.Bioprocess and biosystems engineering · 2025Review
- The Role of Nanoparticles in Accelerating Tissue Recovery and Inflammation Control in Physiotherapy Practices.Cureus · 2024Review
- Review
- Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis.BioImpacts : BI · 2024Article
- Chitosan nanoparticle applications in dentistry: a sustainable biopolymer.Frontiers in chemistry · 2024Review
- Advances in haemostatic sponges: Characteristics and the underlying mechanisms for rapid haemostasis.Bioactive materials · 2023Review
- Properties and biotechnological applications of microbial deacetylase.Applied microbiology and biotechnology · 2023Review
- Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review.Frontiers in chemistry · 2023Review
- Extraction and Characterization of Chitin and Chitosan fromAdvanced biomedical research · 2023Article
- Application Progress of Modified Chitosan and Its Composite Biomaterials for Bone Tissue Engineering.International journal of molecular sciences · 2022Review
- Article
- Use of micro-grafts in a chronic infected open wound after limb amputation in a cat.Veterinarni medicina · 2021Article
- The effect of chemical and structural modifiers on the haemostatic process and cytotoxicity of the beta-chitin patch.Scientific reports · 2021Article
- Nanoclay/Polymer-Based Hydrogels and Enzyme-Loaded Nanostructures for Wound Healing Applications.Gels (Basel, Switzerland) · 2021Review
- Chitosan-Based Nanocomposite Polymeric Membranes for Water Purification-A Review.Materials (Basel, Switzerland) · 2021Review
- Antimicrobial Actions and Applications of Chitosan.Polymers · 2021Review
- Isolation and characterization of chitosan from Ugandan edible mushrooms, Nile perch scales and banana weevils for biomedical applications.Scientific reports · 2021Article
- Progress and challenges in the synthesis of sequence controlled polysaccharides.Beilstein journal of organic chemistry · 2021Review
Corrections and comments
- Retraction · 2018-06-07Plagiarism of/in Article ·
- Retracted
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitin (β-(1-4)-poly-N-acetyl-D-glucosamine) is widely distributed in nature and is the second most abundant polysaccharide after cellulose. It is often converted to its more deacetylated derivative, chitosan. Previously, many reports have indicated the accelerating effects of chitin, chitosan, and its derivatives on wound healing. More recently, chemically modified or nano-fibrous chitin and chitosan have been developed, and their effects on wound healing have been evaluated. In this review, the studies on the wound-healing effects of chitin, chitosan, and its derivatives are summarized. Moreover, the development of adhesive-based chitin and chitosan are also described. The evidence indicates that chitin, chitosan, and its derivatives are beneficial for the wound healing process. More recently, it is also indicate that some nano-based materials from chitin and chitosan are beneficial than chitin and chitosan for wound healing. Clinical applications of nano-based chitin and chitosan are also expected.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.