ArticleBiomedical optics express2015
Broadband absorption and reduced scattering spectra of in-vivo skin can be noninvasively determined using δ-P1 approximation based spectral analysis.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- LoGoReg-Net: local-global feature aggregation regularized unrolling network for functional brain imaging via high-density DOT.Biomedical optics express · 2026Article
- Frequency domain broadband short-wave infrared spectroscopy for measurement of tissue optical properties from 685 to 1300 nm.Journal of biomedical optics · 2025Article
- Effect of skin color on optical properties and the implications for medical optical technologies: a review.Journal of biomedical optics · 2024Review
- Relevance and utility of theBiomedical optics express · 2023Review
- Tissue Phantoms for Biomedical Applications in Raman Spectroscopy: A Review.Biomedical engineering and computational biology · 2020Review
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Authors and funding
4 authors.
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Abstract
Previously, we revealed that a linear gradient line source illumination (LGLSI) geometry could work with advanced diffusion models to recover the sample optical properties at wavelengths where sample absorption and reduced scattering were comparable. In this study, we employed the LGLSI geometry with a broadband light source and utilized the spectral analysis to determine the broadband absorption and scattering spectra of turbid samples in the wavelength range from 650 to 1350 nm. The performance of the LGLSI δ-P1 diffusion model based spectral analysis was evaluated using liquid phantoms, and it was found that the sample optical properties could be properly recovered even at wavelengths above 1000 nm where μs' to μa ratios were in the range between 1 to 20. Finally, we will demonstrate the use of our system for recovering the 650 to 1350 nm absorption and scattering spectra of in-vivo human skin. We expect this system can be applied to study deep vessel dilation induced hemoglobin concentration variation and determine the water and lipid concentrations of in-vivo skin in clinical settings in the future.
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