Evidence map›Paper›PMID 25780667›Full record

ArticleJournal of pharmacopuncture2013

Anti-Allergic Effect of Ulmus davidiana Cortex on Contact Dermatitis Induced by Dinitrofluoro- Benzene in Mice.

Jeonghyeon Lyu, Byung-Joo Kim, Hyungwoo Kim

Open access · diamondAbstract read
In one paragraph

Article in Journal of pharmacopuncture, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Polyphenols from the Root Barks ofInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeonghyeon LyuDivision of Pharmacology, Pusan National University School of Korean Medicine, Yangsan, Korea.
Byung-Joo KimDivision of Longevity and Biofunctional Medicine, Pusan National University School of Korean Medicine, Yangsan, Korea.
Hyungwoo KimDivision of Pharmacology, Pusan National University School of Korean Medicine, Yangsan, Korea.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe root bark of Ulmus davidiana var. Japonica (Ulmi Radicis cortex, URC) is a medicinal herb used for promoting diuresis and treating dampness. In Korea, URC has long been used as an efficacious therapy for inflammation, burns, frostbite and skin diseases such as eczema and psoriasis.

methodsIn the present study, we used 1-fluoro-2,4- dinitrofluorobenzene (DNFB)-induced contact dermatitis (CD) mouse model to investigate the antiallergic and the anti-inflammatory effects of URC on skin lesion, histopathological changes and specific antibody production.

resultsURC treatment, 10 mg/mL, effectively inhibited skin lesions induced by repeated paintings with DNFB. In the histopathological observation, topical application of URC inhibited spongiosis. In addition, URC lowered the production levels of total immunoglobulin and IgG2a in serum.

conclusionThese data indicate that URC has an anti-inflammatory effect that produces an improvement of skin lesions in CD mice.

Indexed as

allergydermatitisinflammationskinUlmus davidiana

Identifiers

PMID25780667
PMCPMC4331966
OpenAlexW2133740019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.