Evidence map›Paper›PMID 25780626›Full record

ArticleCanadian journal of kidney health and disease2015

Validating a scoring tool to predict acute kidney injury (AKI) following cardiac surgery.

Brian Wong, Jennifer St Onge, Stephen Korkola, Bhanu Prasad

Abstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian WongCollege of Medicine - Regina Campus, University of Saskatchewan, Regina General Hospital, 1440-14th Avenue, Regina, SK S4P0W5 Canada.
Jennifer St OngeResearch and Performance Support, Regina Qu'Appelle Health Region, Regina, SK, 2180 - 23rd Avenue, Regina, SK S4S 0A5 Canada.
Stephen KorkolaDepartment of Surgery, Regina Qu'Appelle Health Region, Regina, SK, Regina General Hospital, 1440-14th Avenue, Regina, SK S4P0W5 Canada.
Bhanu PrasadSection of Nephrology, Department of Medicine, Regina Qu'Appelle Health Region, Regina, SK, Regina General Hospital, 1440-14th Avenue, 3401-B Pasqua Street, Regina, SK S4P0W5 Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) after cardiac surgery is associated with an increased risk of mortality. Preoperative risk scores can identify patients at risk for AKI and facilitate preventive strategies. Currently, validated risk scores are used to predict AKI requiring dialysis (AKI-D); less is known about whether these tools predict less severe forms of AKI.

objectiveTo evaluate the Cleveland Clinic scoring tool in predicting both AKI-D and less severe stages of AKI in patients after cardiac surgery in a Canadian tertiary care center.

designRetrospective case-control study.

settingRegina Qu'Appelle Health Region (RQHR) from 2007 to 2011. PATIENTS: Patients who underwent cardiac surgery and developed postoperative kidney injury (n = 2316). MEASUREMENTS: Data on risk factors for AKI and outcomes of cardiac surgery were collected from a retrospective chart review.

methodsThe primary outcome was AKI, defined as Stage 1 (increase in serum creatinine 1.5-1.9 X baseline within 5 days), Stage 2 (increase 2.0-2.9 X baseline), or Stage 3 (increase 3.0 X baseline or more OR initiation of dialysis during hospital stay). We assessed the performance of a modified version of the Cleveland Clinic tool using receiver operating curve analyses.

resultsThe incidence of AKI was 6.1% (Stage 1), 2.6% (Stage 2), and 5.8% (Stage 3). The area under the curve (AUC) for the Cleveland score was 0.61 (95% CI: 0.56 to 0.65; p < 0.001) for Stage 1, 0.61 (95% CI: 0.54 to 0.68; p < 0.01) for Stage 2, and 0.78 (95% CI: 0.74 to 0.82; p < 0.001) for Stage 3. Greater level of risk on the Cleveland tool was associated with a higher risk of Stage 3 AKI. LIMITATIONS: Lack of prospective validation.

conclusionsThe modified Cleveland Clinic tool was valid in identifying patients with severe stages of AKI but did not have strong discrimination for early AKI stages.

Indexed as

Acute kidney injuryCardiac surgery complicationDialysisMortalitySerum creatinine

Identifiers

PMID25780626
PMCPMC4349478

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.