Evidence map›Paper›PMID 25780394›Full record

ArticleExperimental and therapeutic medicine2015

Role of tissue transglutaminase in the pathogenesis of diabetic cardiomyopathy and the intervention effect of rutin.

Hai-Cheng Gao, Kun Zhu, Hai-Mei Gao, Chun-Sheng Miao, LE-Ning Zhang, Wei Liu, Hua Xin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hai-Cheng GaoDepartment of Clinical Pharmacy and Pharmaceutical Management, Jilin University, Changchun, Jilin 130021, P.R. China.
Kun ZhuDepartment of Endocrinology, The 208th Hospital of PLA, Changchun, Jilin 130000, P.R. China.
Hai-Mei GaoPatient's Information Recording Room, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.
Chun-Sheng MiaoDepartment of Clinical Pharmacy and Pharmaceutical Management, Jilin University, Changchun, Jilin 130021, P.R. China.
LE-Ning ZhangDepartment of Chest Surgery, The China-Japan Union Hospital of Jilin University, Changchun, Jilin 130000, P.R. China.
Wei LiuDepartment of Endocrinology, The 208th Hospital of PLA, Changchun, Jilin 130000, P.R. China.
Hua XinDepartment of Chest Surgery, The China-Japan Union Hospital of Jilin University, Changchun, Jilin 130000, P.R. China.
Jilin University · CNChangchun 208 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the role of tissue transglutaminase (tTG) in the pathogenesis of diabetic cardiomyopathy (DCM) and the intervention effect of rutin. DCM was induced in rats by the injection of streptozotocin (STZ; 25 mg/kg). After a preliminary examination, the rats were randomly divided into four groups: Control (n=8), STZ-induced DCM (n=8), STZ + positive drug (captopril; n=6) and STZ + rutin (n=8) groups. The DCM model was evaluated using blood sugar values, serum enzyme levels, hematoxylin and eosin staining and Masson's staining,

Indexed as

diabeticdiabetic cardiomyopathyrutintissue transglutaminase

Identifiers

PMID25780394
PMCPMC4353750
OpenAlexW2057186692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.