Evidence map›Paper›PMID 25780316›Full record

ReviewWorld journal of gastroenterology2015

Primary hepatic neuroendocrine tumor with multiple liver metastases: A case report with review of the literature.

Kai Yang, Ying-Sheng Cheng, Ji-Jin Yang, Xu Jiang, Ji-Xiang Guo

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kai YangKai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201306, China.
Ying-Sheng ChengKai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201306, China.
Ji-Jin YangKai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201306, China.
Xu JiangKai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201306, China.
Ji-Xiang GuoKai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 201306, China.
Shanghai Sixth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein present a case involving a 41-year-old woman in whom ultrasound examination revealed multiple liver hemangiomas more than 3 years ago. Follow-up ultrasound examination revealed that the masses had significantly increased; the largest was located in the right lobe (about 8.2 cm × 7.4 cm × 6.0 cm). Abdominal multidetector computed tomography revealed multiple well-circumscribed, heterogeneous, hypodense masses (largest, 6.4 cm × 6.3 cm × 5.0 cm) with significant contrast enhancement during the arterial and portal phases and with contrast wash-out and peripheral enhancement during the delayed phases. Magnetic resonance images demonstrated multiple well-circumscribed, heterogeneous, hypointense hepatic masses with significant contrast enhancement (largest, 6.4 cm × 6.5 cm × 5.1 cm); multiple enlarged porta lymph nodes; and multiple slightly enlarged retroperitoneal lymph nodes. Histological and immunohistochemical examination of the right mass biopsy specimen suggested a malignant neoplasm that had originated from a neuroendocrine cell type (grade 2 well-differentiated neuroendocrine carcinoma). After performing a systemic examination to exclude metastasis from an extrahepatic primary site, we considered that the masses had arisen from a primary hepatic neuroendocrine tumor with multiple liver metastases. The patient underwent transcatheter arterial chemoembolization using a combination of oxaliplatin (150 mg) mixed with one bottle of gelatin sponge particles (560-710 μm) and lipiodol (6 mL). Primary neuroendocrine tumors of the liver are extremely rare. This case is interesting because of the rarity of this neoplasm and previous misdiagnosis as multiple liver hemangiomas. Previously reported cases in the literature are also reviewed.

Indexed as

AdultAntineoplastic AgentsBiomarkers, TumorBiopsyChemoembolization, TherapeuticDiagnostic ErrorsEthiodized OilFemaleGelatinHemangiomaHumansImmunohistochemistryLiver NeoplasmsLymphatic MetastasisMagnetic Resonance ImagingMultidetector Computed TomographyAntineoplastic AgentsBiomarkers, TumorEthiodized OilGelatinOrganoplatinum CompoundsOxaliplatinImagingImmunohistochemicalLiverMetastaticNeoplasms - primaryNeuroendocrine tumorTranscatheter arterial chemoembolization

Identifiers

PMID25780316
PMCPMC4356938
OpenAlexW2019334105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.