ReviewWorld journal of gastroenterology2015
Cutaneous metastasis of cholangiocarcinoma.
Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Cutaneous metastases from intrahepatic cholangiocarcinoma: a case report.Discover oncology · 2026Article
- Ectopic β-hCG-Expressing Hepatic Neoplasm with Cutaneous Metastasis in a Young Postpartum Woman: A Case Report and Literature Review.International journal of women's health · 2026Article
- Orbital metastasis in advanced gallbladder and biliary tract malignancy.BMJ case reports · 2025Article
- Non-iatrogenic implantation of cutaneous metastasis from hepatocellular carcinoma.Journal of cancer research and clinical oncology · 2023Article
- Comparison analysis of PD-1/PD-L1 inhibitors plus lenvatinib or gemcitabine/cisplatin as first-line treatment for patients with advanced intrahepatic cholangiocarcinoma.Frontiers in oncology · 2023Article
- Laparoscopic versus open hepatectomy for intrahepatic cholangiocarcinoma in patients aged 60 and older: a retrospective cohort study.World journal of surgical oncology · 2022Article
- Cutaneous Metastasis from Cholangiocarcinoma.Chonnam medical journal · 2022Article
- Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis.Life (Basel, Switzerland) · 2021Article
- Intrahepatic Cholangiocarcinoma Presenting as a Scalp Mass.Journal of gastrointestinal cancer · 2020Article
- Cutaneous Cholangiocarcinoma: An Interesting Presentation.Plastic and reconstructive surgery. Global open · 2020Article
- Cutaneous scalp metastasis of cholangiocarcinoma in hepatitis C.JAAD case reports · 2020Article
- Cutaneous erysipeloid metastasis of cholangiocarcinoma and evaluation by in vivo reflectance confocal microscopy.JAAD case reports · 2018Article
- Isolated implant metastasis in chest wall due to seeding of transpleurally placed PTBD catheter tract in a case of hilar cholangiocarcinoma.BMJ case reports · 2017Article
- Cutaneous Metastasis from Cholangiocarcinoma Presenting as Thigh Mass.Journal of clinical and diagnostic research : JCDR · 2016Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the clinical characteristics and prognostic factors of cutaneous metastasis of cholangiocarcinoma by a retrospective analysis of published cases.
methodsAn extensive search was conducted in the English literature within the PubMed database using the following keywords: cutaneous metastasis or skin metastasis and cholangiocarcinoma or bile duct. The data of 30 patients from 21 articles from 1978 to 2014 were analyzed. Patient data retrieved from the articles included the following: age, gender, time cutaneous metastasis occurred, number of cutaneous metastases throughout life, sites of initial cutaneous metastasis, anatomic site, pathology and differentiation of cholangiocarcinoma, and immunohistochemical results of the cutaneous metastasis. The assessment of overall survival after cutaneous metastasis (OSCM) was the primary endpoint.
resultsThe median age at diagnosis of cutaneous metastasis of cholangiocarcinoma was 60.0 years (range: 35-77). This metastasis showed a predilection towards males, with a male to female ratio of 3.29. In 8 cases (27.6%), skin metastasis was the first sign of cholangiocarcinoma. Additionally, 18 cases (60.0%) manifested single cutaneous metastasis, while 12 cases (40.0%) demonstrated multiple skin metastases. In 50.0% of patients, the metastasis occurred in the drainage region, while 50.0% of patients had distant cutaneous metastases. The scalp was the most frequently involved region of distant skin metastasis, occurring in 36.7% of patients. The median OSCM of cholangiocarcinoma was 4.0 mo. Patient age and cutaneous metastatic sites showed no significant relation with OSCM, while male gender and single metastasis of the skin were associated with a poorer OSCM (hazard ratio: 0.168; P = 0.005, and hazard ratio: 0.296; P = 0.011, respectively).
conclusionThe prognosis of cutaneous metastasis of cholangiocarcinoma is dismal. Both male gender and single skin metastasis are associated with a poorer OSCM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.