Evidence map›Paper›PMID 25780271›Full record

ArticleExperimental mechanics2015

Optimization of a lensless digital holographic otoscope system for transient measurements of the human tympanic membrane.

I Dobrev, C Furlong, J T Cheng, J J Rosowski

Abstract read
In one paragraph

Article in Experimental mechanics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

I DobrevCenter for Holographic Studies and Laser micro-mechaTronics - CHSLT Department of Mechanical Engineering, Worcester Polytechnic Institute, Worcester MA 01609.
C FurlongCenter for Holographic Studies and Laser micro-mechaTronics - CHSLT Department of Mechanical Engineering, Worcester Polytechnic Institute, Worcester MA 01609 ; Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston MA 02114 ; Department of Otology and Laryngology, Harvard Medical School, Boston, MA USA.
J T ChengEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston MA 02114 ; Department of Otology and Laryngology, Harvard Medical School, Boston, MA USA.
J J RosowskiEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston MA 02114 ; Department of Otology and Laryngology, Harvard Medical School, Boston, MA USA.

Funding

Computer-based Holography and Middle-Ear FunctionR01DC008642 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI ROSOWSKI, JOHN J · 2007 to 2014
$2.2M
NIDCD NIH HHS R01 DC008642
6 · The paper itself

Abstract

In this paper, we propose a multi-pulsed double exposure (MPDE) acquisition method to quantify in full-field-of-view the transient (i.e., >10 kHz) acoustically induced nanometer scale displacements of the human tympanic membrane (TM or eardrum). The method takes advantage of the geometrical linearity and repeatability of the TM displacements to enable high-speed measurements with a conventional camera (i.e., <20 fps). The MPDE is implemented on a previously developed digital holographic system (DHS) to enhance its measurement capabilities, at a minimum cost, while avoiding constraints imposed by the spatial resolutions and dimensions of high-speed (i.e., >50 kfps) cameras. To our knowledge, there is currently no existing system to provide such capabilities for the study of the human TM. The combination of high temporal (i.e., >50 kHz) and spatial (i.e., >500k data points) resolutions enables measurements of the temporal and frequency response of all points across the surface of the TM simultaneously. The repeatability and accuracy of the MPDE method are verified against a Laser Doppler Vibrometer (LDV) on both artificial membranes and ex-vivo human TMs that are acoustically excited with a sharp (i.e., <100 μs duration) click. The measuring capabilities of the DHS, enhanced by the MPDE acquisition method, allow for quantification of spatially dependent motion parameters of the TM, such as modal frequencies, time constants, as well as inferring local material properties.

Indexed as

Acoustic-solid interactionHigh-speed digital holographyMiniaturization engineeringOtologyTransient responseTympanic membrane

Identifiers

PMID25780271
PMCPMC4358780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.