ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2015
Umbilical and fetal middle cerebral artery Doppler at 35-37 weeks' gestation in the prediction of adverse perinatal outcome.
Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.
- Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Cerebroplacental ratio and middle cerebral artery doppler indices as associations with maternal and neonatal outcomes in term pregnancies undergoing labor induction or augmentation: A cross-sectional study.European journal of obstetrics & gynecology and reproductive biology: X · 2026Article
- Longitudinal Assessment of Third-Trimester Fetal Biometry and Cerebroplacental Ratio for Predicting Adverse Perinatal Outcomes in an Unselected Obstetric Population: A Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Impact of doppler reference chart selection on risk stratification in fetal growth restriction.BMC pregnancy and childbirth · 2026Article
- Article
- Fetal and maternal surveillance in high-risk pregnancy: tools, timing, and trends.Journal of medicine and life · 2025Review
- Diagnosis, Prevention, and Management of Fetal Growth Restriction (FGR).Journal of personalized medicine · 2024Review
- Association of Cerebroplacental Ratio by Colour Doppler with Perinatal Outcome in Near Term and Term Foetuses.Journal of obstetrics and gynaecology of India · 2023Article
- Intrauterine Growth Restriction-Prediction and Peripartum Data on Hospital Care.Medicina (Kaunas, Lithuania) · 2023Article
- Comparison of renal artery Doppler parameters of monochorionic diamniotic twin pregnancies with and without twin-to-twin transfusion syndrome.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Uteroplacental-Cerebral Ratio: A Doppler Parameter for Prognostic Prediction of Late-Onset Fetal Growth Restriction: Single Center Prospective Cohort Study.Journal of clinical medicine · 2022Article
- Perinatal and 2-year neurodevelopmental outcome in late preterm fetal compromise: the TRUFFLE 2 randomised trial protocol.BMJ open · 2022Article
- Perinatal Adverse Effects in Newborns with Estimated Loss of Weight Percentile between the Third Trimester Ultrasound and Delivery. The GROWIN Study.Journal of clinical medicine · 2021Article
- The correlation between the cerebroplacental ratio and fetal arterial blood gas in appropriate-for-gestational-age fetuses: A cross-sectional study.International journal of reproductive biomedicine · 2021Article
- Cerebroplacental ratio as predictor of adverse perinatal outcome in the third trimester.Acta obstetricia et gynecologica Scandinavica · 2021Article
- Role of sFlt-1/PlGF ratio and feto-maternal Doppler for the prediction of adverse perinatal outcome in late-onset pre-eclampsia.Archives of gynecology and obstetrics · 2020Article
- Prediction of neonatal acidosis using the cerebroplacental ratio at different gestational weeks: A case-control study.Medicine · 2019Article
- Reduced fetal growth velocities and the association with neonatal outcomes in appropriate-for-gestational-age neonates: a retrospective cohort study.BMC pregnancy and childbirth · 2019Article
- Cross-validated prediction model for severe adverse neonatal outcomes in a term, non-anomalous, singleton cohort.BMJ paediatrics open · 2019Article
- Utility of Doppler parameters at 36-42 weeks' gestation in the prediction of adverse perinatal outcomes in appropriate-for-gestational-age fetuses.Journal of ultrasonography · 2018Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the potential value of cerebroplacental ratio (CPR) at 36 weeks' gestation in the prediction of adverse perinatal outcome.
methodsThis was a screening study in 6178 singleton pregnancies at 35-37 weeks' gestation. Umbilical artery (UA) and fetal middle cerebral artery (MCA) pulsatility index (PI) were measured and the values were converted to multiples of the median (MoM) after adjustment from variables in maternal characteristics and medical history that affect the measurements. CPR was calculated by dividing MCA-PI MoM by UA-PI MoM. Multivariable logistic regression analysis was used to determine if measuring CPR improved the prediction of adverse perinatal outcome provided by maternal characteristics, medical history and obstetric factors. The detection rate (DR) and false-positive rate (FPR) of screening by CPR were estimated for stillbirth, Cesarean section for fetal distress, umbilical arterial cord blood pH ≤ 7.0, umbilical venous cord blood pH ≤ 7.1, 5-min Apgar score < 7 and admission to the neonatal unit (NNU) and neonatal intensive care unit (NICU).
resultsThere was a linear association between CPR and both birth-weight Z-score and arterial or venous umbilical cord blood pH, but the steepness of the regression lines was inversely related to the interval from assessment to delivery. The performance of low CPR < 5(th) percentile in screening for each adverse outcome was poor, with DRs of 6-15% and a FPR of about 6%. In the small subgroup of the population delivering within 2 weeks of assessment, the DRs improved to 14-50%, but with a simultaneous increase in FPR, to about 10%.
conclusionThe performance of CPR in routine screening for adverse perinatal outcome at 36 weeks' gestation is poor.
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