ArticleThyroid : official journal of the American Thyroid Association2015
Sociodemographic disparities in differentiated thyroid cancer survival among adolescents and young adults in California.
Article in Thyroid : official journal of the American Thyroid Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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43 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum.Cancer medicine · 2022Pooled it
- Global health inequities in thyroid cancer among adolescents and young adults from overdiagnosis to inadequate care by the socio-demographic index.Global health research and policy · 2026Article
- Disparities in Rural-Urban Cancer Care Outcomes among Pediatric, Adolescent, and Young Adult Populations: A Comprehensive Narrative Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Review
- The role of rurality and race/ethnicity in thyroid cancer stage at diagnosis and survival among adolescents and young adults in the United States: an analysis of 2000-2021 SEER data.Cancer causes & control : CCC · 2026Article
- Differentiated Thyroid Cancer Recurrence and Mortality Prognostic Factors: A Retrospective Cohort Study on 350 Adult Patients.Iranian journal of otorhinolaryngology · 2026Article
- Neighborhood factors associated with late effects among survivors of adolescent and young adult cancer.Journal of cancer survivorship : research and practice · 2025Article
- A Cuproptosis-Related gene Signature as a Prognostic Biomarker in Thyroid Cancer Based on Transcriptomics.Biochemical genetics · 2025Article
- Disparities in Thyroid Cancer Mortality Across Racial and Ethnic Groups: Assessing the Impact of Socioeconomic, Clinicopathologic, and Treatment Variations.Annals of surgical oncology · 2025Article
- Article
- The Multi-Institutional Medullary Thyroid Cancer Collaborative Registry: Can a Rare Tumor Registry Accurately Represent the Real-World Patient Population?Thyroid : official journal of the American Thyroid Association · 2024Article
- Neighborhood-level social determinants of health burden among adolescent and young adult cancer patients and impact on overall survival.JNCI cancer spectrum · 2024Article
- Racial and Ethnic Disparities in the Diagnosis and Treatment of Thyroid Disease.The Journal of clinical endocrinology and metabolism · 2024Review
- Characterization of Thyroid Cancer among Hispanics in California, USA, from 2010 to 2020.Cancers · 2024Article
- Survival Trends Among Adolescents and Young Adults Diagnosed With Cancer in the United States: Comparisons With Children and Older Adults.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Review
- Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes.Frontiers in public health · 2024Article
- Challenges and Opportunities of Epidemiological Studies to Reduce the Burden of Cancers in Young Adults.Current epidemiology reports · 2023Article
- Social Determinants of Health and Quality of Life in Endocrine Surgery Patients.The Journal of surgical research · 2023Article
- Comparison of ultrasonography and pathology features between children and adolescents with papillary thyroid carcinoma.Heliyon · 2023Article
- The Impact of Hospital Surgical Volume on Healthcare Utilization Outcomes After Pediatric Thyroidectomy.World journal of surgery · 2022Article
- Financial Hardship by Age at Diagnosis Including in Young Adulthood among African American Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundFew studies have focused on prognostic factors among adolescents and young adults (AYAs) 15 to 39 years of age when diagnosed with differentiated thyroid cancer (DTC). Our study expands upon prior work by including an evaluation of survival among AYA men and by neighborhood socioeconomic status, health insurance, and clinical factors to identify subgroups of young DTC patients at higher risk of mortality.
methodsData for 16,827 AYA DTC patients diagnosed between 1988 and 2010 were obtained from the California Cancer Registry. Survival, through 2010, by sociodemographic and clinical factors was analyzed using Cox proportional hazards regression.
resultsOf the 2.1% of AYAs who died, 16.7% died from thyroid cancer and 21.4% died from a subsequent cancer. In multivariate analyses, older AYAs 35 to 39 year of age (versus 15- to 29-year-olds), men (hazard ratio [HR] 2.77, 95% confidence interval [CI] 1.62-4.72), and AYAs of African American or Hispanic race/ethnicity (versus non-Hispanic whites) had worse thyroid cancer specific survival. In addition, residing in low socioeconomic status neighborhoods (HR 3.11 [CI 1.28-7.56]) and nonmetropolitan areas (HR 5.53 [CI 2.07-14.78]) was associated with worse thyroid cancer-specific survival among AYA men, but not AYA women.
conclusionsDespite the generally good prognosis among AYAs with DTC, we identified subgroups of AYA patients at risk for poor outcomes. Further study of the factors underlying these associations, including possible barriers to receiving high-quality treatment and follow-up care, as well as lifestyle factors, are critical to reducing these disparities.
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