ReviewWiley interdisciplinary reviews. Systems biology and medicine
The role of the microbiota in ageing: current state and perspectives.
Review in Wiley interdisciplinary reviews. Systems biology and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Patchouli Ethanol ExtractAging medicine (Milton (N.S.W)) · 2025Article
- Changes in oral health during aging in a novel non-human primate model.GeroScience · 2024Article
- Gut Microbiota: Critical Controller and Intervention Target in Brain Aging and Cognitive Impairment.Frontiers in aging neuroscience · 2021Review
- Mitochondrial Dynamics in Stem Cells and Differentiation.International journal of molecular sciences · 2018Review
- Characterization of the urinary microbiota of elderly women and the effects of type 2 diabetes and urinary tract infections on the microbiota.Oncotarget · 2017Article
- Review
- Decoding host-microbiota communication in the gut - now we're flying!The Journal of physiology · 2017Article
- ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases.Oxidative medicine and cellular longevity · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledSince the application of high-throughput technologies to investigate complex microbial communities, alterations in the human gut microbiota have been associated with an increasing number of diseases and conditions. This field of research has developed into an area of intense study which is quite different to the microbial investigations that have preceded it in terms of both the broadness of the area of research and the complexity of the analyses. In this review, we discuss gut microbiota changes observed in ageing in the context of the physiological changes that accompany senescence, examine what correlations can be established or inferred, and we discuss what key questions remain to be answered in the field. WIREs Syst Biol Med 2015, 7:131-138. doi: 10.1002/wsbm.1293 For further resources related to this article, please visit the WIREs website. CONFLICT OF INTEREST: PWOT is funded by a nonrestrictive research award from General Mills Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.