ArticleProceedings of the National Academy of Sciences of the United States of America2015
Allelic polymorphism of GIGANTEA is responsible for naturally occurring variation in circadian period in Brassica rapa.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Review
- The Roles of Circadian Clock Genes in Plant Temperature Stress Responses.International journal of molecular sciences · 2024Review
- Environmental F actors coordinate circadian clock function and rhythm to regulate plant development.Plant signaling & behavior · 2023Review
- The Circadian Clock Coordinates the Tradeoff between Adaptation to Abiotic Stresses and Yield in Crops.Biology · 2023Review
- Gene-by-environment interactions in plants: Molecular mechanisms, environmental drivers, and adaptive plasticity.The Plant cell · 2023Review
- SOS1 safeguards plant circadian rhythm against daily salt fluctuations.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The circadian clock ticks in plant stress responses.Stress biology · 2022Review
- GIpred: a computational tool for prediction of GIGANTEA proteins using machine learning algorithm.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- TheGenes · 2021Article
- A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis).BMC plant biology · 2021Article
- Review
- The Photoperiod: Handling and Causing Stress in Plants.Frontiers in plant science · 2021Review
- Comparative Transcriptome Analysis of Early- and Late-Bolting Traits in Chinese Cabbage (Frontiers in genetics · 2021Article
- Review
- Interspecific analysis of diurnal gene regulation in panicoid grasses identifies known and novel regulatory motifs.BMC genomics · 2020Article
- Genetic and physiological mechanisms of freezing tolerance in locally adapted populations of a winter annual.American journal of botany · 2020Article
- Circadian Rhythms in Plants.Cold Spring Harbor perspectives in biology · 2019Review
- Evolution of Cold Acclimation and Its Role in Niche Transition in the Temperate Grass Subfamily Pooideae.Plant physiology · 2019Article
- QTL Underlying Circadian Clock Parameters Under Seasonally Variable Field Settings inG3 (Bethesda, Md.) · 2019Article
- Article
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13 authors.
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Abstract
GIGANTEA (GI) was originally identified by a late-flowering mutant in Arabidopsis, but subsequently has been shown to act in circadian period determination, light inhibition of hypocotyl elongation, and responses to multiple abiotic stresses, including tolerance to high salt and cold (freezing) temperature. Genetic mapping and analysis of families of heterogeneous inbred lines showed that natural variation in GI is responsible for a major quantitative trait locus in circadian period in Brassica rapa. We confirmed this conclusion by transgenic rescue of an Arabidopsis gi-201 loss of function mutant. The two B. rapa GI alleles each fully rescued the delayed flowering of Arabidopsis gi-201 but showed differential rescue of perturbations in red light inhibition of hypocotyl elongation and altered cold and salt tolerance. The B. rapa R500 GI allele, which failed to rescue the hypocotyl and abiotic stress phenotypes, disrupted circadian period determination in Arabidopsis. Analysis of chimeric B. rapa GI alleles identified the causal nucleotide polymorphism, which results in an amino acid substitution (S264A) between the two GI proteins. This polymorphism underlies variation in circadian period, cold and salt tolerance, and red light inhibition of hypocotyl elongation. Loss-of-function mutations of B. rapa GI confer delayed flowering, perturbed circadian rhythms in leaf movement, and increased freezing and increased salt tolerance, consistent with effects of similar mutations in Arabidopsis. Collectively, these data suggest that allelic variation of GI-and possibly of clock genes in general-offers an attractive target for molecular breeding for enhanced stress tolerance and potentially for improved crop yield.
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