Evidence map›Paper›PMID 25775486›Full record

ArticleIEEE transactions on medical imaging2015

Higher-Order Motion-Compensation for In Vivo Cardiac Diffusion Tensor Imaging in Rats.

Christopher L Welsh, Edward V R DiBella, Edward W Hsu

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
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  6. Simultaneous non-contrast assessment of cardiac microstructure and perfusion in vivo in the human heart.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
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  11. On the possibility of estimating myocardial fiber architecture from cardiac strains.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2023
    Article
  12. Diffusion-weighted imaging and diffusion tensor imaging of the heartPostepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2022
    Review
  13. Article
  14. Myocardial mesostructure and mesofunction.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  15. Article
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  19. Cardiovascular magnetic resonance imaging of functional and microstructural changes of the heart in a longitudinal pig model of acute to chronic myocardial infarction.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  20. Myofiber strain in healthy humans using DENSE and cDTI.Magnetic resonance in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christopher L Welsh
Edward V R DiBella
Edward W Hsu
University of Utah · US

Funding

UTAH SMALL ANIMAL MRI RESEARCH RESOURCE: PHARMACEUTICALSS10RR023017 · NCRR · UNIVERSITY OF UTAH · PI HSU, EDWARD W · 2006 to 2006
$1.7M
Atlas-Based Structural Models of the Mouse MyocardiumR01HL092055 · NHLBI · UNIVERSITY OF UTAH · PI HSU, EDWARD W · 2009 to 2012
$1.5M
Rapid high order diffusion imaging for strokeR01NS083761 · NINDS · UNIVERSITY OF UTAH · PI DIBELLA, EDWARD VR · 2013 to 2016
$1.4M
NCRR NIH HHS S10 RR023017NHLBI NIH HHS R01 HL092055NINDS NIH HHS R01 NS08376NINDS NIH HHS R01 NS083761
6 · The paper itself

Abstract

Motion of the heart has complicated in vivo applications of cardiac diffusion MRI and diffusion tensor imaging (DTI), especially in small animals such as rats where ultra-high-performance gradient sets are currently not available. Even with velocity compensation via, for example, bipolar encoding pulses, the variable shot-to-shot residual motion-induced spin phase can still give rise to pronounced artifacts. This study presents diffusion-encoding schemes that are designed to compensate for higher-order motion components, including acceleration and jerk, which also have the desirable practical features of minimal TEs and high achievable b-values. The effectiveness of these schemes was verified numerically on a realistic beating heart phantom, and demonstrated empirically with in vivo cardiac diffusion MRI in rats. Compensation for acceleration, and lower motion components, was found to be both necessary and sufficient for obtaining diffusion-weighted images of acceptable quality and SNR, which yielded the first in vivo cardiac DTI demonstrated in the rat. These findings suggest that compensation for higher order motion, particularly acceleration, can be an effective alternative solution to high-performance gradient hardware for improving in vivo cardiac DTI.

Indexed as

AnimalsBlood PressureCardiac Imaging TechniquesDiffusion Tensor ImagingHeartImage Processing, Computer-AssistedMaleRatsRats, Sprague-Dawley

Identifiers

PMID25775486
PMCPMC4560625
OpenAlexW2092295159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.