Evidence map›Paper›PMID 25775440›Full record

ArticleClinical obstetrics and gynecology2015

Caring for Opioid-dependent Pregnant Women: Prenatal and Postpartum Care Considerations.

Elizabeth E Krans, Gerald Cochran, Debra L Bogen

Registry-linked trialAbstract read
In one paragraph

Article in Clinical obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03098407 (A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03098407 nacompletednot on this mapstarted 2017, after this paper: background citation

A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.

TypeinterventionalSponsorUniversity of PittsburghRan2017 to 2020Enrolled55ConditionsOpioid-Related Disorders, PregnancyArmsBuprenorphine, Methadone
3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Associations between maternal opioid use disorder treatment and pregnancy outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Limited bedding and nesting increases ethanol drinking in female rats.Pharmacology, biochemistry, and behavior · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Increasing access to immediate postpartum contraceptive implants: a prospective clinical trial among patients with opioid use disorder.The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Postpartum contraceptive planning of women with substance abuse disorders.International journal of clinical pharmacy · 2021
    Article
  16. Multilevel factors associated with length of stay for neonatal abstinence syndrome in Florida's NICUs: 2010-2015.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth E KransDepartments of *Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Research Institute ‡Pediatrics †School of Social Work, University of Pittsburgh, Pittsburgh, Pennsylvania.
Gerald Cochran
Debra L Bogen

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
NCATS NIH HHS KL2 TR000146
6 · The paper itself

Abstract

Pregnancy is an opportune time to identify opioid dependence, facilitate conversion to opioid maintenance treatment, and coordinate care with specialists in addiction medicine, behavioral health, and social services. Comprehensive prenatal care for opioid-dependent women involves the evaluation and the management of co-occurring psychiatric disorders, polysubstance use, infectious diseases, social stressors, and counseling regarding the importance of breastfeeding, contraception, and neonatal abstinence syndrome. Although the complex psychiatric, social, and environmental factors faced by this population pose significant challenges to obstetric care providers, the development of strong patient-provider relationships can facilitate the ability to deliver efficient and effective health care during pregnancy.

Indexed as

Alcohol-Related DisordersNeonatal Abstinence SyndromeOpioid-Related DisordersPregnancy ComplicationsBreast FeedingCounselingFemaleHumansIncidenceInfant, NewbornMethadoneNarcoticsOpiate Substitution TreatmentPregnancyPrenatal CareSmokingMethadoneNarcotics

Identifiers

PMID25775440
PMCPMC4607033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.