Evidence map›Paper›PMID 25775227›Full record

ArticleJournal of medicinal food2015

Inhibitory Effects of Two Varieties of Tunisian Pomegranate (Punica granatum L.) Extracts on Gastrointestinal Transit in Rat.

Abdelaziz Souli, Hichem Sebai, Kais Rtibi, Latifa Chehimi, Mohsen Sakly, Mohamed Amri, Jamel El-Benna, Lamjed Marzouki

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal food, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Anti-Cholera toxin activity of selected polyphenols fromFrontiers in cellular and infection microbiology · 2023
    Article
  2. Pomegranate: A review of the heavenly healer's past, present, and future.Iranian journal of basic medical sciences · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Abdelaziz Souli1 Laboratory of Nutrition and Animal Physiology, Higher Institute of Biotechnology of Beja , Beja, Tunisia .
Hichem Sebai1 Laboratory of Nutrition and Animal Physiology, Higher Institute of Biotechnology of Beja , Beja, Tunisia .
Kais Rtibi1 Laboratory of Nutrition and Animal Physiology, Higher Institute of Biotechnology of Beja , Beja, Tunisia .
Latifa Chehimi3 Laboratory of Integrated Physiology, Faculty of Sciences of Bizerte , Zarzouna, Tunisia .
Mohsen Sakly3 Laboratory of Integrated Physiology, Faculty of Sciences of Bizerte , Zarzouna, Tunisia .
Mohamed Amri2 Laboratory of Neurophysiology and Functional Pathology, Department of Biological Sciences, Faculty of Sciences of Tunis , Tunis, Tunisia .
Jamel El-Benna4 INSERM U1149 Biomedical Research Centre, Faculty of Medicine X . Bichat, Paris, France .
Lamjed Marzouki2 Laboratory of Neurophysiology and Functional Pathology, Department of Biological Sciences, Faculty of Sciences of Tunis , Tunis, Tunisia .
Tunis University · TNUniversity of Carthage · TNCzech Academy of Sciences, Institute of Biotechnology · CZInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was undertaken to determine whether total and methanol juice extracts of two Tunisian Pomegranate (Punica granatum L.) varieties (Garsi and Gabsi) protect against diarrhea as well as their effects on gastrointestinal transit (GIT) in healthy rats. In this respect, male Wistar rats were used and divided into control- and pomegranate-treated groups. The antidiarrheal activity was evaluated using the castor oil-induced diarrhea method and the GIT was assessed using charcoal meal. Our results showed that total and methanol P. granatum juice extracts produced a significant dose-dependent protection against castor oil-induced diarrhea. Pomegranate extracts and juice also decreased the GIT significantly and dose dependently. Importantly, the Garsi variety appeared to be more effective than the Gabsi variety on these two parameters. These findings suggest that pomegranate extracts have a potent antidiarrheal property in rats confirming their efficiency in the Tunisian traditional medicine.

Indexed as

LythraceaePhytotherapyAnimalsAntidiarrhealsCastor OilDiarrheaFruitFruit and Vegetable JuicesGastrointestinal TransitMaleMedicine, African TraditionalPlant ExtractsRats, WistarSpecies SpecificityTunisiaAntidiarrhealsCastor OilPlant Extractsdiarrheagastrointestinal transitmineralspomegranaterat

Identifiers

PMID25775227
PMCPMC4580143
OpenAlexW1780655349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.