Evidence map›Paper›PMID 25775186›Full record

ReviewCurrent opinion in rheumatology2015

State of the evidence.

Kelli D Allen, Yvonne M Golightly

2 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 193 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed, 7 pooled it
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03663790 narecruitingnot on this mapstarted 2018, after this paper: background citation

Comparison of the Effects of Gait Modification Strategies on Knee Adduction Moment in Patients With Medial Knee Osteoarthritis: Randomized Controlled Trial

TypeinterventionalSponsorGeorge Mason UniversityRan2018 to 2026Enrolled51ConditionsKnee OsteoarthritisArmsFoot Progression, Trunk Lean
NCT04061733 naunknown statusnot on this mapstarted 2019, after this paper: background citation

New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis

TypeinterventionalSponsorPromedonRan2019 to 2024Enrolled50ConditionsOsteoarthritis, Knee, PainArmsHydrogel injection
3 · Its place in the literature

Who cites it

193 citing papers in PubMed, 7 syntheses or guidelines pooled it, 397 citations in OpenAlex.

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  3. Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
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133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kelli D AllenaThurston Arthritis Research Center bDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill cDepartment of Veterans Affairs Medical Center, Center for Health Services Research in Primary Care, Durham dDepartment of Epidemiology eInjury Prevention Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Yvonne M Golightly
University of North Carolina at Chapel Hill · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
NCATS NIH HHS KL2 TR001109NCATS NIH HHS KL2TR001109NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1TR001111NCATS NIH HHS UL1 TR002489
6 · The paper itself

Abstract

purpose of reviewThis review focuses on recent studies of osteoarthritis epidemiology, including research on prevalence, incidence, and a broad array of potential risk factors at the person level and joint level. RECENT

findingsStudies continue to illustrate the high impact of osteoarthritis worldwide, with increasing incidence. Person-level risk factors with strong evidence regarding osteoarthritis incidence and/or progression include age, sex, socioeconomic status, family history, and obesity. Joint-level risk factors with strong evidence for incident osteoarthritis risk include injury and occupational joint loading; the associations of injury and joint alignment with osteoarthritis progression are compelling. Moderate levels of physical activity have not been linked to increased osteoarthritis risk. Some topics of high recent interest or emerging evidence for association with osteoarthritis include metabolic pathways, vitamins, joint shape, bone density, limb length inequality, muscle strength and mass, and early structural damage. SUMMARY: Osteoarthritis is a complex, multifactorial disease, and there is still much to learn regarding mechanisms underlying incidence and progression. However, there are several known modifiable and preventable risk factors, including obesity and joint injury; efforts to mitigate these risks can help to lessen the impact of osteoarthritis.

Indexed as

Disease ProgressionGlobal HealthHumansMorbidityOsteoarthritis

Identifiers

PMID25775186
PMCPMC4405030
OpenAlexW2091418075

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.